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Lesinurad Impurity J

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Lesinurad Impurity J Basic information

Product Name:
Lesinurad Impurity J
Synonyms:
  • 2-((5-bromo-4-(naphthalen-1-yl)-4H-1,2,4-triazol-3-yl)thio)acetic acid
  • Lesinurad Impurity 9 (Lesinurad Impurity E)
  • Lesinurad Impurity J
  • Lesinurad Impurity 1/2-[[5-Bromo-4-(naphthalen-1-yl)-4H-1,2,4-triazol-3-yl]thio]-acetic Acid
  • Resinad Impurity I: Decyclocycloresinad
  • Acetic acid, 2-[[5-bromo-4-(1-naphthalenyl)-4H-1,2,4-triazol-3-yl]thio]-
CAS:
1210330-64-5
MF:
C14H10BrN3O2S
MW:
364.22
Mol File:
1210330-64-5.mol
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Lesinurad Impurity J Chemical Properties

Boiling point:
617.6±57.0 °C(Predicted)
Density 
1.69±0.1 g/cm3(Predicted)
pka
2.91±0.10(Predicted)
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Lesinurad Impurity J Usage And Synthesis

Uses

2-[[5-Bromo-4-(naphthalen-1-yl)-4H-1,2,4-triazol-3-yl]thio]-acetic Acid is an impurity of drug Lesinurad (L329700), which is used to synthesize febuxostat which is a non-purine analog inhibitor of xanthine oxidase. Febuxostat is approved by the European Medicines Agency and the US Food and Drug Administration for treating gout.

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