Basic information Safety Supplier Related

PROPOXYPHENE HYDROCHLORIDE

Basic information Safety Supplier Related

PROPOXYPHENE HYDROCHLORIDE Basic information

Product Name:
PROPOXYPHENE HYDROCHLORIDE
Synonyms:
  • DARVON
  • DEXTROPROPOXYPHENE HYDROCHLORIDE
  • Propoxyphene Hydrochloride CII (1 g)
  • QMQBBUPJKANITL-MYXGOWFTSA-N
  • PROPOXYPHENE HYDROCHLORIDE
  • (+)-1,2-diphenyl-2-propionoxy-3-methyl-4-dimethylaminobutanehydrochloride
  • D-PROPOXYPHENE HCL NARCOTIC ANALGESIC
  • (aS)-a-[(1R)-2-(Dimethylamino)-1-methylethyl]-a-phenylbenzeneethanol Propanoate Hydrochloride
CAS:
1639-60-7
MF:
C22H29NO2.ClH
MW:
375.93
EINECS:
216-683-5
Product Categories:
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
  • Amines
  • Aromatics
Mol File:
1639-60-7.mol
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PROPOXYPHENE HYDROCHLORIDE Chemical Properties

Melting point:
165-1670C
alpha 
D25 +59.8° (c = 0.6 in water)
Flash point:
11 °C
storage temp. 
-20°C Freezer
solubility 
Very soluble in water, freely soluble in ethanol (96 per cent).
Water Solubility 
3.7mg/L(25 ºC)
CAS DataBase Reference
1639-60-7(CAS DataBase Reference)
EPA Substance Registry System
Propoxyphene hydrochloride (1639-60-7)
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Safety Information

Hazard Codes 
F,T
Risk Statements 
11-23/24/25-39/23/24/25
Safety Statements 
16-36/37-45
RIDADR 
3249
HazardClass 
6.1(b)
PackingGroup 
III
Toxicity
LD50 in mice, rats (mg/kg): 28, 15 i.v.; 111, 58 i.p.; 211, 134 s.c.; 282, 230 orally (Emerson)
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PROPOXYPHENE HYDROCHLORIDE Usage And Synthesis

Chemical Properties

White Solid

Uses

Dextropropoxyphene is a controlled substance (narcotic)

Uses

Dextropropoxyphene is a controlled substance (opiate). Analgesic (narcotic). The α-dl-and d-diastereoisomers possess marked analgesic activity in contrast to the β-diastereoisomers which are substantially inactive.

brand name

Darvon (Xanodyne); Dolene (Clonmel).

Safety Profile

A human poison by ingestion. An experimental poison by ingestion, intraperitoneal, subcutaneous, intravenous, and intramuscular routes. Human systemic effects by ingestion: anorexia, ataxia, chronic pulmonary edema, cyanosis, increased body temperature, jaundice, nausea or vomiting, sleep disturbance. Experimental teratogenic and reproductive effects. When heated to decomposition it emits very toxic fumes of HCl and NOx. See also PROPOXYPHENE.

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