3-Chloro-5-(trifluoromethyl)pyridin-2-amine Chemical Properties

Melting point:

86-90 °C (lit.)

Boiling point:

205°C

Density 

1.4650 (estimate)

vapor pressure 

40.8Pa at 24.85℃

storage temp. 

under inert gas (nitrogen or Argon) at 2–8 °C

solubility 

Chloroform (Slightly), Methanol (Slightly)

pka

1.79±0.49(Predicted)

form 

Crystalline Powder

color 

White to off-white

Water Solubility 

622mg/L at 25℃

InChIKey

WXNPZQIRDCDLJD-UHFFFAOYSA-N

LogP

2.59 at 20℃

CAS DataBase Reference

79456-26-1(CAS DataBase Reference)

Safety Information

Hazard Codes 

Xn,Xi

Risk Statements 

22-52/53-36/37/38-20/21/22

Safety Statements 

61-36/37/39-26-22

WGK Germany 

2

HazardClass 

IRRITANT

HS Code 

29339900

MSDS

• Language:English Provider:SigmaAldrich

3-Chloro-5-(trifluoromethyl)pyridin-2-amine Usage And Synthesis

Chemical Properties

Light yellow Cryst

Uses

2-?Amino-?3-?chloro-?5-?trifluoromethylpyrid?ine acts as a reactant in the synthesis of novel imidazo[1,2-a]pyridine-coumarin hybrid molecules as inhibitors of NS5B in potential treatment of Hepititis C.

Definition

ChEBI: 3-Chloro-5-(trifluoromethyl)pyridin-2-amine is an aminopyridine.

3-Chloro-5-(trifluoromethyl)pyridin-2-amine(79456-26-1)Related Product Information

• 2-Chloro-5-chloromethylpyridine
• Glycine
• Tris(hydroxymethyl)aminomethane
• Betaine
• 3-Aminopyridine
• Aniline
• Bis(2-ethylhexyl)amine
• 4-Methylpyridine
• 2-Aminopyridine
• 2-Amino-3-picoline
• 2-Chloro-5-trifluoromethylpyridine
• 4-Dimethylaminopyridine
• Epichlorohydrin
• ALTRENOGEST
• Chloroacetic acid
• Difluorochloromethane
• 3-AMINO-2-CHLORO-6-(TRIFLUOROMETHYL)PYRIDINE, 97% MIN.,3-AMINO-2-CHLORO-6-(TRIFLUOROMETHYL)PYRIDINE,2-CHLORO-6-(TRIFLUOROMETHYL)PYRIDIN-3-AMINE
• Trifluoromethyl