Ethyl 6-Hydroxyhexanoate Chemical Properties

Boiling point:

127-128 °C/12 mmHg (lit.)

Density 

0.985 g/mL at 25 °C (lit.)

refractive index 

n20/D 1.437(lit.)

Flash point:

>230 °F

storage temp. 

Sealed in dry,Room Temperature

form 

clear liquid

pka

15.15±0.10(Predicted)

color 

Colorless to Almost colorless

InChI

InChI=1S/C8H16O3/c1-2-11-8(10)6-4-3-5-7-9/h9H,2-7H2,1H3

InChIKey

HYXRUZUPCFVWAH-UHFFFAOYSA-N

SMILES

C(OCC)(=O)CCCCCO

LogP

0.917 (est)

Safety Information

WGK Germany 

3

HS Code 

2918.19.9000

MSDS

• Language:English Provider:SigmaAldrich

Ethyl 6-Hydroxyhexanoate Usage And Synthesis

Uses

Ethyl 6-Hydroxyhexanoate is used as a reagent in the synthesis of cross-reactive carbohydrate determinants (CCDs) as tools for in vitro allergy diagnosis. Ethyl 6-Hydroxyhexanoate is also used in the preparation of N-5-Carboxypentyl-1-deoxymannojirimycin (C181150); a ligand used for the preparation of an affinity resin specific for Man9 mannosidase.

Uses

Ethyl 6-hydroxyhexanoate is suitable for use in the synthesis of series of model phenol carbonate ester prodrugs having fatty acid-like structures. It may be used in the preparation of alkyl triflates. It may be used in the synthesis of ethyl 6-(trifluoromethylsulfonyloxy)hexanoate.

Synthesis Reference(s)

The Journal of Organic Chemistry, 38, p. 2786, 1973 DOI: 10.1021/jo00956a011
Synthetic Communications, 11, p. 599, 1981 DOI: 10.1080/00397918108063631

General Description

Ethyl 6-hydroxyhexanoate is an ethyl ester. Its concentration in bordeaux red wines has been evaluated. Two-step preparation of ethyl 6-hydroxyhexanoate via hydrolysis of e-caprolactone has been reported.

Ethyl 6-Hydroxyhexanoate(5299-60-5)Related Product Information

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