Basic information Safety Supplier Related

methyl 2-(4-hydroxy-1-methyl-7-phenoxyisoquinoline-3-carboxamido)acetate

Basic information Safety Supplier Related

methyl 2-(4-hydroxy-1-methyl-7-phenoxyisoquinoline-3-carboxamido)acetate Basic information

Product Name:
methyl 2-(4-hydroxy-1-methyl-7-phenoxyisoquinoline-3-carboxamido)acetate
Synonyms:
  • ROXA-022
  • methyl 2-(4-hydroxy-1-methyl-7-phenoxyisoquinoline-3-carboxamido)acetate
  • Glycine, N-[(4-hydroxy-1-methyl-7-phenoxy-3-isoquinolinyl)carbonyl]-, methyl ester
  • Roxadustat Impurity 9
  • Roxadustat Methyl Ester
  • methyl (4-hydroxy-1-methyl-7-phenoxyisoquinoline-3-carbonyl)glycinate
  • Roxadustat Impurities4
  • Roxadustat Impurity 2Q: What is Roxadustat Impurity 2 Q: What is the CAS Number of Roxadustat Impurity 2
CAS:
1421312-36-8
MF:
C20H18N2O5
MW:
366.37
Mol File:
1421312-36-8.mol
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methyl 2-(4-hydroxy-1-methyl-7-phenoxyisoquinoline-3-carboxamido)acetate Chemical Properties

InChI
InChI=1S/C20H18N2O5/c1-12-16-10-14(27-13-6-4-3-5-7-13)8-9-15(16)19(24)18(22-12)20(25)21-11-17(23)26-2/h3-10,24H,11H2,1-2H3,(H,21,25)
InChIKey
QSGJZCCNTOCDRI-UHFFFAOYSA-N
SMILES
C(OC)(=O)CNC(C1=C(O)C2=C(C(C)=N1)C=C(OC1=CC=CC=C1)C=C2)=O
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methyl 2-(4-hydroxy-1-methyl-7-phenoxyisoquinoline-3-carboxamido)acetate Usage And Synthesis

Uses

Roxadustat Methyl Ester is used in the preparation of Roxadustat.Roxadustat (H948180) is a hypoxia-inducible factor (HIF) prolyl hydroxylase inhibitor used to increase white blood cell levels in blood and hematopoietic progenitor cells in bone marrow.It is used for treatment of anemia in patient with chronic kidney disease.

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