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3-hydroxybutyric acid

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3-hydroxybutyric acid Basic information

Product Name:
3-hydroxybutyric acid
Synonyms:
  • RARECHEM AL BO 1231
  • DL-3-HYDROXY-N-BUTYRIC ACID
  • DL-BETA-HYDROXYBUTYRIC ACID
  • BETA-HYDROXY-N-BUTYRIC ACID
  • 3 HBA
  • 3-hydroxy-butanoicaci
  • beta-hydroxybutyrate
  • Butanoic acid, 3-hydroxy-
CAS:
300-85-6
MF:
C4H8O3
MW:
104.1
EINECS:
206-099-9
Product Categories:
  • Functional Materials
  • Hydroxycarboxylic Acids (for High-Performance Polymer Research)
  • Reagent for High-Performance Polymer Research
  • Building Blocks
  • C1 to C5
  • Carbonyl Compounds
  • API intermediates
  • Carboxylic Acids
  • Chemical Synthesis
  • Organic Building Blocks
Mol File:
300-85-6.mol
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3-hydroxybutyric acid Chemical Properties

Melting point:
174-175℃
Boiling point:
118-120 °C2 mm Hg(lit.)
Density 
1.126 g/mL at 25 °C(lit.)
refractive index 
n20/D 1.443(lit.)
Flash point:
>230 °F
storage temp. 
Inert atmosphere,2-8°C
solubility 
ethanol: soluble50mg/mL, clear
form 
Liquid
pka
4.36±0.10(Predicted)
color 
Colorless
Water Solubility 
Soluble in water, alcohol, ether
Sensitive 
Hygroscopic
Merck 
14,4816
BRN 
773861
LogP
-0.764 (est)
CAS DataBase Reference
300-85-6(CAS DataBase Reference)
EPA Substance Registry System
Butanoic acid, 3-hydroxy- (300-85-6)
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Safety Information

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
RIDADR 
UN 3265 8 / PGII
WGK Germany 
3
10
TSCA 
Yes
HS Code 
29181990

MSDS

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3-hydroxybutyric acid Usage And Synthesis

Chemical Properties

CLEAR COLOURLESS TO LIGHT YELLOW VISCOUS LIQUID

Uses

Industrially, 3-hydroxybutanoic acid is used for the manufacture of biodegradable plastics. It is also acts as a solvent in organoleptics, cosmetics. It is also used in enantioselective synthesis of D-(-)-3-hydroxybutyric acid by Escherichia coli.

Definition

ChEBI: 3-hydroxybutyric acid is a straight-chain 3-hydroxy monocarboxylic acid comprising a butyric acid core with a single hydroxy substituent in the 3- position; a ketone body whose levels are raised during ketosis, used as an energy source by the brain during fasting in humans. Also used to synthesise biodegradable plastics. It has a role as a human metabolite. It is a 3-hydroxy monocarboxylic acid, a hydroxybutyric acid and an (omega-1)-hydroxy fatty acid. It is functionally related to a butyric acid. It is a conjugate acid of a 3-hydroxybutyrate.

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