5-FLUORO-2-METHOXY-[1-[2-[(METHYLSULFONYL)AMINO]ETHYL]-4-PIPERIDINYL]-1H-INDOLE-3-METHYLCARBOXYLATE SULFAMATE
5-FLUORO-2-METHOXY-[1-[2-[(METHYLSULFONYL)AMINO]ETHYL]-4-PIPERIDINYL]-1H-INDOLE-3-METHYLCARBOXYLATE SULFAMATE Basic information
- Product Name:
- 5-FLUORO-2-METHOXY-[1-[2-[(METHYLSULFONYL)AMINO]ETHYL]-4-PIPERIDINYL]-1H-INDOLE-3-METHYLCARBOXYLATE SULFAMATE
- Synonyms:
-
- [1-[2-[(METHYLSULFONYL)AMINO]ETHYL]-4-PIPERIDINYL]METHYL 5-FLUORO-2-METHOXY-1H-INDOLE-3-CARBOXYLATE SULFAMATE SALT
- 5-FLUORO-2-METHOXY-[1-[2-[(METHYLSULFONYL)AMINO]ETHYL]-4-PIPERIDINYL]-1H-INDOLE-3-METHYLCARBOXYLATE SULFAMATE
- GR 125487 SULFAMATE
- GR 125487 SULFAMATE SALT
- 5-Fluoro-2-methoxy-[1-[2-[(methylsulfonyl)amino]ethyl]-4-piperidinyl]-1H-indole-3-methylcarboxylatesulfamate
- 5-fluoro-2-Methoxy-1H-Indole-3-carboxylic acid-[1-[2-[(Methylsulfonyl)aMino]ethyl]-4-piperidinyl]Methyl ester
- GR 125487
- (1-(2-(Methylsulfonamido)ethyl)piperidin-4-yl)-methyl 5-fluoro-2-methoxy-1H-indole-3-carboxylate
- CAS:
- 144625-67-2
- MF:
- C19H26FN3O5S
- MW:
- 427.49
- Mol File:
- 144625-67-2.mol
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5-FLUORO-2-METHOXY-[1-[2-[(METHYLSULFONYL)AMINO]ETHYL]-4-PIPERIDINYL]-1H-INDOLE-3-METHYLCARBOXYLATE SULFAMATE Chemical Properties
- Melting point:
- 118-120℃
- Boiling point:
- 613.4±65.0 °C(Predicted)
- Density
- 1.313±0.06 g/cm3(Predicted)
- storage temp.
- Sealed in dry,2-8°C
- solubility
- H2O: ~14 mg/mL at 60 °C, soluble
- form
- solid
- pka
- 11.22±0.40(Predicted)
- color
- off-white
MSDS
- Language:English Provider:SigmaAldrich
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5-FLUORO-2-METHOXY-[1-[2-[(METHYLSULFONYL)AMINO]ETHYL]-4-PIPERIDINYL]-1H-INDOLE-3-METHYLCARBOXYLATE SULFAMATE Usage And Synthesis
Uses
GR 125487 Sulfamate is potent, selective 5-HT4 antagonist; active in vivo.
Biological Activity
Potent and selective 5-HT 4 receptor antagonist (K i = 0.19 nM for porcine 5-HT 4 ). Centrally active following systemic administration in vivo .
5-FLUORO-2-METHOXY-[1-[2-[(METHYLSULFONYL)AMINO]ETHYL]-4-PIPERIDINYL]-1H-INDOLE-3-METHYLCARBOXYLATE SULFAMATESupplier
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