6-Methylnicotinic acid Chemical Properties

Melting point:

210-213 °C (lit.)

Boiling point:

251.96°C (rough estimate)

Density 

1.2528 (rough estimate)

refractive index 

1.5030 (estimate)

storage temp. 

Inert atmosphere,Room Temperature

solubility 

DMSO (Slightly), Methanol (Slightly)

form 

Powder, Crystals and/or Chunks

pka

2.37±0.10(Predicted)

color 

White to light yellow to beige

Water Solubility 

Sparingly soluble in water.

BRN 

112049

InChI

InChI=1S/C7H7NO2/c1-5-2-3-6(4-8-5)7(9)10/h2-4H,1H3,(H,9,10)

InChIKey

RZOKQIPOABEQAM-UHFFFAOYSA-N

SMILES

C1=NC(C)=CC=C1C(O)=O

CAS DataBase Reference

3222-47-7(CAS DataBase Reference)

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

37/39-26-36

WGK Germany 

3

HazardClass 

IRRITANT

HS Code 

29333990

MSDS

• Language:English Provider:ACROS
• Language:English Provider:SigmaAldrich
• Language:English Provider:ALFA

6-Methylnicotinic acid Usage And Synthesis

Chemical Properties

6-Methylnicotinic acid is a white to light yellow to light orange powder to crystals with a melting point of 210 °C. Store under inert gas at room temperature.

Uses

6-Methylnicotinic acid is an intermediate of the drug etoricoxib (a non- steroidal anti-inflammatory drug for the treatment of arthritis and osteoarthritis). It is also used as organic intermediates.

Uses

A degradation product of Nicotinic acid (N429250). An impurity of Nicotinic acid.

General Description

The co-ordination complex of the formula [Ni(L1)₂(H₂O)₄].4H₂O where L1H = 6-methylpyridine-3-carboxylic acid was structurally charaterized using X-ray single crystal analysis.

6-Methylnicotinic acid(3222-47-7)Related Product Information

• Methyl 6-methylnicotinate
• 2,5-PYRIDINEDICARBOXYLIC ACID
• N,N-Dimethylpropionamide
• 2,2-Dimethylbutyryl chloride
• 2-Phenylbutyric acid
• Etoricoxib
• Etoricoxib Impurity 15
• (Z)-1-(6-methylpyridin-3-yl)-2-(4-(methylsulfonyl)phenyl)ethanone oxime
• Etoricoxib Impurity 7
• Etoricoxib Impurity 39
• Etoricoxib Impurity M
• 2-Chloro-1,3-bis(dimentylamino)trimethinium hexafluorophosphate
• Etoricoxib impurity Q
• 4-(methylsulfinyl)benzeneacetic acid
• Etoricoxib Impurity 8
• Etoricoxib Impurity 13
• 4-Methylthiophenylacetic acid
• 1-(6-Methylpyridin-3-yl)-2-(4-(Methylthio)phenyl)ethanone