13,14-DIHYDRO PROSTAGLANDIN F2ALPHA
13,14-DIHYDRO PROSTAGLANDIN F2ALPHA Basic information
- Product Name:
- 13,14-DIHYDRO PROSTAGLANDIN F2ALPHA
- Synonyms:
-
- 13,14-dihydro PGF2a
- (5Z,15S)-9α,11α,15-Trihydroxyprosta-5-ene-1-oic acid
- 13,14-dihydrodinoprost
- 13,14-dihydro-pgf2-alpha
- 7-(3,5-dihydroxy-2-(3-hydroxyoctyl)cyclopentyl)-5-heptenoicaci
- 7-(3,5-dihydroxy-2-(3-hydroxyoctyl)cyclopentyl)-5-heptenoicacid
- (E)-7-[3,5-dihydroxy-2-(3-hydroxyoctyl)cyclopentyl]hept-5-enoic acid
- LLQBSJQTCKVWTD-NFUXFLSFSA-N
- CAS:
- 27376-74-5
- MF:
- C20H36O5
- MW:
- 356.5
- Mol File:
- 27376-74-5.mol
13,14-DIHYDRO PROSTAGLANDIN F2ALPHA Chemical Properties
- storage temp.
- Store at -20°C
- solubility
- 10 mM Na2CO3: >6.5 mg/ml (from PGF2a); DMF: >100 mg/ml (from PGF2a); DMSO: >100 mg/ml (from PGF2a); Ethanol: >100 mg/ml (from PGF2a); PBS pH 7.2: >10 mg/ml (from PGF2a)
13,14-DIHYDRO PROSTAGLANDIN F2ALPHA Usage And Synthesis
Description
13,14-
Uses
13,14-Dihydro-PGF2α is an analog of PGF2α which has no unsaturation in the lower side chain. It facilitates luteolysis in hamsters/rabbits with potency five times higher than PGF2α.
Definition
ChEBI: A prostaglandins Falpha that is prost-5-en-1-oic acid substituted by hydroxy groups at positions 9, 11 and 15.
References
[1] NIELS H. ANDERSEN. Molecular basis for prostaglandin potency. III. Tests of the significance of the “hairpin conformation” in biorecognition phenomena[J]. Prostaglandins, 1981, 22 5: Pages 841-856. DOI: 10.1016/0090-6980(81)90222-7
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