2-Naphthoic acid Chemical Properties

Melting point:

185-187 °C(lit.)

Boiling point:

300 °C

Density 

1.08

refractive index 

1.5520 (estimate)

Flash point:

205 °C

storage temp. 

Sealed in dry,Room Temperature

solubility 

alcohol: soluble

form 

Powder

pka

4.17(at 25℃)

color 

White to beige

PH

4.5 (H2O, 20℃)

Water Solubility 

<0.5 g/L (20 C)

Merck 

14,6382

BRN 

972039

InChIKey

UOBYKYZJUGYBDK-UHFFFAOYSA-N

CAS DataBase Reference

93-09-4(CAS DataBase Reference)

NIST Chemistry Reference

2-Naphthalenecarboxylic acid(93-09-4)

EPA Substance Registry System

2-Naphthalenecarboxylic acid (93-09-4)

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-36-24/25-36/373/39

WGK Germany 

2

RTECS 

QL1050000

TSCA 

Yes

HS Code 

29163900

MSDS

• Language:English Provider:2-Naphthalenecarboxylic acid
• Language:English Provider:ACROS
• Language:English Provider:SigmaAldrich
• Language:English Provider:ALFA

2-Naphthoic acid Usage And Synthesis

Chemical Properties

Colorless solid

Uses

2-Naphthoic acid is an unprotected acid undergoes lithiation, e.g. with s-BuLi, by stereospecific 1,4-addition, providing a facile route to 1,2,2-trisubstituted 1,2-dihydronaphthalenes. It is also used as an intermediate in organic synthesis. The fluorescence spectra and electronic absorption of 2-naphthoic acid was studied.

Definition

ChEBI: 2-naphthoic acid is a naphthoic acid that is naphthalene carrying a carboxy group at position 2. It has a role as a xenobiotic metabolite and a mouse metabolite. It is a conjugate acid of a 2-naphthoate.

General Description

2-Naphthoic acid (NPA) is a noncompetitive N-methyl-D-aspartate (NMDA) receptor inhibitor. The fluorescence spectra and electronic absorption of 2-naphthoic acid was studied.

Purification Methods

Crystallise the acid from EtOH (4mL/g), aqueous 50% EtOH or Me2CO (m 185-186o). Dry it at 100o. The acid chloride has m 52-52o (from *C6H6/pet ether) and b 160-162o/11mm [Hersberg & Carson Org Synth Coll Vol III 629 1955], the amide has m 192o (from EtOH), and the N-Methyl amide has m 109-109.5o (form *C6H6). [Beilstein 9 H 656, 9 III 3174, 9 IV 2402.]

2-Naphthoic acid(93-09-4)Related Product Information

• Benzyl benzoate
• Glycine
• Ethyl 2-(Chlorosulfonyl)acetate
• Folic acid
• 2,4-Dichlorobenzoic acid
• 1,4-Dihydroxy-2-naphthoic acid
• 2,3,4-Trihydroxybenzoic acid
• Retinoic acid
• Benzoic acid
• 1-Hydroxy-2-naphthoic acid
• DIMETHYL 2,6-NAPHTHALENEDICARBOXYLATE
• 2,6-NAPHTHALENEDICARBOXYLIC ACID
• 2-Naphthoic acid, 3-hydroxy-,3-Hydroxy-beta-naphthoic acid
• 3-Amino-2-naphthoic acid
• 2,3-NAPHTHALENEDICARBOXYLIC ACID
• Calconcarboxylic acid
• 3,4,9,10-Perylenetetracarboxylic dianhydride
• α-Naphthoic acid,1-naphthoic acid (alpha)