Basic information Safety Supplier Related

3-[(1S)-1-(Dimethylaminoethyl)]phenol

Basic information Safety Supplier Related

3-[(1S)-1-(Dimethylaminoethyl)]phenol Basic information

Product Name:
3-[(1S)-1-(Dimethylaminoethyl)]phenol
Synonyms:
  • 3-[(1S)1-(DIMETHYLAMINO)ETHYL]PHENOL(INTERMEDIATEOFRIVASTIGMINE)
  • (S)-3-(1-N,N-DIMETHY(AMINO)ETHYL PHENOL
  • (1S)-3-[-1-(Dimethylaminoethyl)]phenol
  • Rivastigmine-3-(1-(dimethylamino)ethyl)phenol
  • (S)-3-(1-N,N-dimethylaminoethyl) phenol
  • (S)-3-1(1-(Dimethylamino)ethylphenol
  • RivastigMine Metabolite (NAP 226-90)
  • 3-[(1(S)-N,N-DiMethylaMino)Ethyl] Phenol
CAS:
139306-10-8
MF:
C10H15NO
MW:
165.23
EINECS:
1308068-626-2
Product Categories:
  • Intermediate of Rivastigmine
  • Metabolite Reference Standard
  • Chiral Reagents
  • Intermediates & Fine Chemicals
  • Metabolites & Impurities
  • Pharmaceuticals
Mol File:
139306-10-8.mol
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3-[(1S)-1-(Dimethylaminoethyl)]phenol Chemical Properties

Melting point:
87-88°C
Boiling point:
241℃
Density 
1.021
Flash point:
97℃
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
solubility 
DMSO (Slightly), Methanol (Slightly)
form 
Solid
pka
9.86±0.10(Predicted)
color 
White to Off-White
InChIKey
GQZXRLWUYONVCP-QMMMGPOBSA-N
CAS DataBase Reference
139306-10-8(CAS DataBase Reference)
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Safety Information

Risk Statements 
36-43
Safety Statements 
26-36/37/39
HS Code 
29222990
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3-[(1S)-1-(Dimethylaminoethyl)]phenol Usage And Synthesis

Description

NAP 226-90 is a metabolite of rivastigmine that is formed by hydrolysis.

Chemical Properties

off-white to pale yellow crysta

Uses

NAP 226-90 (Rivastigmine EP Impurity A; Rivastigmin USP Related Compound C) is a S-Enantiomer metabolite of Rivastigmine, a brain selective acetylcholinesterase inhibitor.

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