2-(2-Chloroethoxy)ethanol Chemical Properties

Boiling point:

79-81 °C5 mm Hg(lit.)

Density 

1.18 g/mL at 25 °C(lit.)

vapor pressure 

22.66Pa at 20℃

refractive index 

n20/D 1.452(lit.)

Flash point:

195 °F

storage temp. 

Keep in dark place,Sealed in dry,Room Temperature

solubility 

SOLUBLE

form 

Liquid

pka

14.34±0.10(Predicted)

color 

Clear

Water Solubility 

SOLUBLE

BRN 

506015

Stability:

Stable. Incompatible with strong oxidizing agents.

InChIKey

LECMBPWEOVZHKN-UHFFFAOYSA-N

LogP

0.301 at 30℃

CAS DataBase Reference

628-89-7(CAS DataBase Reference)

NIST Chemistry Reference

Ethanol, 2-(2-chloroethoxy)-(628-89-7)

EPA Substance Registry System

Ethanol, 2-(2-chloroethoxy)- (628-89-7)

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38-36

Safety Statements 

26-36-39

RIDADR 

UN 3334

WGK Germany 

2

RTECS 

KK1350000

F 

19

TSCA 

Yes

HS Code 

29094990

MSDS

• Language:English Provider:Diethylene glycol monochlorohydrin
• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS
• Language:English Provider:ALFA

2-(2-Chloroethoxy)ethanol Usage And Synthesis

Chemical Properties

colourless liquid

Uses

2-(2-Chloroethoxy)ethanol is a degradation product of Bis(2-Chloroethyl) Ether. 2-(2-Chloroethoxy)ethanol is a potential genotoxic impurity (PGI) in active pharmaceutical ingredients (APIs).

Uses

2-(2-Chloroethoxy)ethanol is employed in the preparation of o-nitrophenylbromoacetaldehyde bis-2-(2-chloroethoxy)-ethyl acetal, quetiapine and 2-(2-azidoethoxy)ethanol.

Uses

2-(2-Chloroethoxy)ethanol was used in the synthesis of o-nitrophenylbromoacetaldehyde bis-2-(2-chloroethoxy)-ethyl acetal, quetiapine (an antipsychotic drug) and 2-(2-azidoethoxy)ethanol.

Flammability and Explosibility

Non flammable

2-(2-Chloroethoxy)ethanol(628-89-7)Related Product Information

• 2-Ethoxyethanol
• 1,4-Butanediol
• 2-Ethoxyphenol
• DIETHOXYMETHANE
• C8E3
• 3-Chloro-1,2-propanediol
• Diethylene glycol diacrylate
• Dipropylene glycol
• Diethylene glycol
• Niclosamide ethanolamine salt
• Ethylene glycol
• 2-Butoxyethanol
• Ethoxyethyne
• 2-Methyl-2,4-pentanediol
• Ethoxyquin
• Ethyl acetate
• Diethylene glycol monobutyl ether
• Phenetidine