Choline hydroxide Chemical Properties

Melting point:

236～239℃

Density 

1.09 g/mL at 20 °C

vapor pressure 

28.284hPa at 25℃

refractive index 

n20/D 1.4304

Flash point:

92 °F

storage temp. 

Inert atmosphere,2-8°C

solubility 

Water (easy), ethanol (difficult to dissolve (1-pentanol)), ether (insoluble)

form 

Granular Powder

pka

13.9(at 25℃)

color 

White

Water Solubility 

miscible

Merck 

14,2204

Stability:

Stable. Combustible. Incompatible with strong oxidizing agents.

InChIKey

KIZQNNOULOCVDM-UHFFFAOYSA-M

LogP

-2.25 at 25℃

CAS DataBase Reference

123-41-1(CAS DataBase Reference)

EPA Substance Registry System

Ethanaminium, 2-hydroxy-N,N,N-trimethyl-, hydroxide (123-41-1)

Safety Information

Hazard Codes 

C,T

Risk Statements 

34-35-43-39/23/24/25-23/24/25-10-R35

Safety Statements 

26-36/37/39-45-S45-S36/37/39-S26

RIDADR 

UN 3286 3/PG 2

WGK Germany 

1

RTECS 

GA4025500

F 

8-9-23

TSCA 

Yes

HazardClass 

8

PackingGroup 

II

HS Code 

29231000

MSDS

• Language:English Provider:ACROS
• Language:English Provider:SigmaAldrich
• Language:English Provider:ALFA

Choline hydroxide Usage And Synthesis

Description

Choline hydroxide or choline base is also known as 2-hydroxyl ethyl trimethyl ammonium hydroxide. It is a strong yet organic base.
Choline hydroxide is primarily used to produce other choline salts, which could be used in nutraceuticals, baby food, etc.  Choline hydroxide can be used as phase transfer catalysts which carry the hydroxide ion into organic systems. It is used as an ingredient in cleaning and developer formulations in the electronics and printed circuit board industry and in paint stripping formulations. It can also be used as corrosion inhibitor, for the H2S removal from gas streams. Furthermore, it is used as the cleaning and degreasing agent in the metal industry.

References

[1] Patent US20160068476: Process for choline hydroxide
[2] https://en.wikipedia.org/wiki/Choline

Chemical Properties

clear light yellow viscous solution

Uses

Choline hydroxide is used as a precursor molecule for the neurotransmitter acetylcholine, it is involved in several functions including muscle and memory muscle control. It was used as a basic catalyst for aldol condensation reactions.

Uses

Choline hydroxide solution has been used in the synthesis of choline hexafluoroacetylacetonate that can be used as an extractant along with bis-(trifluoromethylsulfonyl)imide ionic liquid for the homogeneous liquid-liquid extraction of neodymium(III).

Definition

An amino alcohol,CH₂OHCH₂N(CH₃)₃OH. It occurswidely in living organisms as aconstituent of certain types ofphospholipids– the lecithins andsphingomyelins– and in the neurotransmitteracetylcholine. It issometimes classified as a memberof the vitamin B complex.

Flammability and Explosibility

Non flammable

Choline hydroxide(123-41-1)Related Product Information

• Benzyltrimethylammonium hydroxide
• Tetramethylammonium hydroxide pentahydrate
• Sodium hydroxide
• Tetraethylammonium hydroxide
• Aluminum hydroxide
• 2-(METHYLSULFONYL)ETHANOL
• Hydroxyethyl Cellulose
• Ammonium hydroxide
• Sodium isethionate
• 2-(2-Aminoethylamino)ethanol
• Tetraethylammonium bromide
• Lithium hydroxide monohydrate
• Hydroxyethyl starch
• Citicoline sodium
• choline,tartrate(1:1)sal
• Lecithin
• 1-CYCLOHEXYL-3-(2-MORPHOLINOETHYL)CARBODIIMIDE METHO-P-TOLUENESULFONATE
• TETRAETHANOL AMMONIUM HYDROXIDE
• Choline Hydroxide Solution