2-Methylthiophene Chemical Properties

Melting point:

-63 °C (lit.)

Boiling point:

113 °C (lit.)

Density 

1.014 g/mL at 25 °C (lit.)

vapor pressure 

47.6 mm Hg ( 37.7 °C)

refractive index 

n20/D 1.52(lit.)

Flash point:

45 °F

storage temp. 

2-8°C

solubility 

immiscible

form 

Liquid

Specific Gravity

1.025 (20℃)

color 

Clear colorless to yellow

Odor

at 0.01 % in propylene glycol. sulfurous alliaceous onion roasted green

Odor Type

sulfurous

Water Solubility 

immiscible

BRN 

103734

InChIKey

XQQBUAPQHNYYRS-UHFFFAOYSA-N

LogP

2.330

CAS DataBase Reference

554-14-3(CAS DataBase Reference)

NIST Chemistry Reference

Thiophene, 2-methyl-(554-14-3)

EPA Substance Registry System

Thiophene, 2-methyl- (554-14-3)

Safety Information

Hazard Codes 

F,Xn,Xi

Risk Statements 

11-22-36/37/38-37-2017/11/22

Safety Statements 

16-37/39-26-36-33-7/9

RIDADR 

UN 1993 3/PG 2

WGK Germany 

3

RTECS 

XM9625000

F 

10-13

TSCA 

T

HazardClass 

3

PackingGroup 

II

HS Code 

29349990

MSDS

• Language:English Provider:2-Methylthiophene
• Language:English Provider:SigmaAldrich
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2-Methylthiophene Usage And Synthesis

Chemical Properties

clear colorless to slightly yellow liquid

Uses

2-Methylthiophene, is used as a flavoring agent that naturally occurs in grilled and roasted beef, papaya, cooked shrimp, whiskey, and in trace amounts in roasted chicken;

Definition

ChEBI: 2-methylthiophene is a member of the class of thiophenes that is thiophene in which the hydrogen atom at position 2 is substituted by a methyl group. It has a role as a flavouring agent and a Maillard reaction product. It is a member of thiophenes and a volatile organic compound. It is functionally related to a thiophene.

Production Methods

2-Methylthiophene is commercially produced to 98 wt% purity by VP cyclization.

Application

2-Methylthiophene is a feasible raw material for the production of several of the important 2-substituted thiophenes. It may be used to manufacture 2-chloromethylthiophene (2-thenyl chloride), but this and further syntheses must be completed in situ, because of its instability.

Synthesis Reference(s)

The Journal of Organic Chemistry, 14, p. 638, 1949 DOI: 10.1021/jo01156a016
Tetrahedron Letters, 22, p. 2443, 1981 DOI: 10.1016/S0040-4039(01)92928-4

2-Methylthiophene(554-14-3)Related Product Information

• Cephalothin sodium
• Tetrahydrothiophene
• Thifensulfuron
• 2-Thiophenecarboxaldehyde
• Cyclopropyl 2-thienyl ketone
• Ethyl 2-thiophenecarboxylate
• 2-Acetylthiophene
• 2-Thiopheneglyoxylic acid
• 2,2'-BITHIOPHENE
• 5-NITROTHIOPHENE-2-CARBOXALDEHYDE
• 3-Methyl-2-thiophenecarboxylic acid
• 2-Thiophenecarboxylic acid hydrazide
• 2-Formyl-5-methylthiophene
• 4-Bromothiophene-2-carboxaldehyde
• 2-Thiophenecarbonitrile
• 3-Methyl-2-thiophenecarboxaldehyde
• 2-Carboxy-5-methylthiophene
• 2-Acetyl-3-methylthiophene