Boc-beta-alanine Chemical Properties

Melting point:

76-78 °C

Boiling point:

333.9±25.0 °C(Predicted)

Density 

1.129±0.06 g/cm3(Predicted)

storage temp. 

Keep in dark place,Sealed in dry,Room Temperature

solubility 

DMSO (Slightly), Methanol (Slightly)

form 

Crystalline Powder

pka

4.46±0.10(Predicted)

color 

White to off-white

BRN 

1909986

InChI

InChI=1S/C8H15NO4/c1-8(2,3)13-7(12)9-5-4-6(10)11/h4-5H2,1-3H3,(H,9,12)(H,10,11)

InChIKey

WCFJUSRQHZPVKY-UHFFFAOYSA-N

SMILES

C(=O)(NCCC(=O)O)OC(C)(C)C

CAS DataBase Reference

3303-84-2(CAS DataBase Reference)

Safety Information

Hazard Codes 

Xn

Risk Statements 

20/21/22-36/37/38

Safety Statements 

22-24/25-36-26

WGK Germany 

3

HazardClass 

IRRITANT

HS Code 

29241990

MSDS

• Language:English Provider:SigmaAldrich
• Language:English Provider:ALFA

Boc-beta-alanine Usage And Synthesis

Description

Boc-beta-Ala-OH is an alkane chain with terminal carboxlic acid and Boc-protected amino groups. The compound can be used as a PROTAC linker in the synthesis of PROTACs. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The Boc group can be deprotected under mild acidic conditions to form the free amine.

Chemical Properties

White solid

Uses

Boc-?β-?Ala-?OH is a reagent used in the synthesis of quinazolines as platelet aggregation inhibitors and ligands of integrin.

reaction suitability

reaction type: Boc solid-phase peptide synthesis

Boc-beta-alanine(3303-84-2)Related Product Information

• Ethyl 2-(Chlorosulfonyl)acetate
• β-Alanine
• Phenprobamate
• tert-Butanol
• N-Carbobenzyloxyglycine
• N-(tert-Butoxycarbonyl)-L-alanine
• EC 2.6.1.2
• L-Alanine
• Folic acid
• D-Alanine
• N-Boc-L-valine
• BOC-D-ALPHA-T-BUTYLGLYCINE
• BOC-L-Prolinol
• BOC-ORN-OH
• Citric acid
• Ascoric Acid
• BOC-D-Alanine
• (BOC-AMINOOXY)ACETIC ACID