DIPERODON HYDROCHLORIDE
DIPERODON HYDROCHLORIDE Basic information
- Product Name:
- DIPERODON HYDROCHLORIDE
- Synonyms:
-
- 3-piperidino-1,2-propanedioldicarbanilatehydrochloride
- diothanehydrochloride
- Diperodon HCl
- 3-(1-PIPERIDINYL)-1,2-PROPANEDIOL BIS(PHENYLCARBAMATE)
- 3-[1-PIPERIDINYL]-1,2-PROPANEDIOL BIS[PHENYLCARBAMATE] HYDROCHLORIDE
- DIPERODON HYDROCHLORIDE
- 1,2-propanediol,3-(1-piperidinyl)-,bis(phenylcarbamato)(ester),monohydroc
- 1,2-propanediol,3-piperidino-,dicarbanilate,hydrochloride
- CAS:
- 537-12-2
- MF:
- C22H28ClN3O4
- MW:
- 433.93
- EINECS:
- 208-659-8
- Product Categories:
-
- TANTUM
- Mol File:
- 537-12-2.mol
DIPERODON HYDROCHLORIDE Chemical Properties
- Melting point:
- 193-201°C
- storage temp.
- Hygroscopic, -20°C Freezer, Under inert atmosphere
- solubility
- Methanol (Slightly)
- form
- Solid
- color
- White
DIPERODON HYDROCHLORIDE Usage And Synthesis
Originator
Diothane Hydrochloride,HMR
Uses
analgesic, antipyretic, antiinflammatory
Uses
Diperodon Hydrochloride is an inhibitor of ebola virus (EBOV) and marburg virus (MARV) by an antiviral activity of the G protein-coupled receptor (GPCR) antagonist.
Manufacturing Process
15.0 g phenylisocyanate in 100 ml of anhydrous ether are added to 10 g of N- (1,2-dihydroxypropyl)-piperidine (prepared from glycide and piperidine) and the solution boiled for two hours, after which it is cooled and saturated with dry hydrogen chloride gas. The ether layer is then decanted off and the remaining insoluble product is dissolved in a hot mixture of acetone and ethyl acetate which on cooling precipitates white crystals of the hydrochloride of the ester of 1,2-propanediol, 3-(1-piperidinyl)-, bis(phenylcarbamate); MP 197°- 198°C. A base form may be prepared by adding an equivalent of triethyl amine.
Therapeutic Function
1,2-Propanediol, 3-(1-piperidinyl)-, bis(phenylcarbamate) (ester), hydrochloride
DIPERODON HYDROCHLORIDESupplier
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DIPERODON HYDROCHLORIDE(537-12-2)Related Product Information
- Palbociclib
- Cloperastine hydrochloride
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- Ropivacaine hydrochloride
- 2-methoxyethyl carbamate
- DIPERODON
- Propham
- HYDROXYPROPYLCARBAMATE
- DIPERODON HYDROCHLORIDE
- 3-PIPERIDINO-1,2-PROPANEDIOL
- 3-(Diethylamino)-1,2-propanediol
- 1-Piperidinepropanol