Basic information Safety Supplier Related

L-(-)-VESAMICOL HYDROCHLORIDE

Basic information Safety Supplier Related

L-(-)-VESAMICOL HYDROCHLORIDE Basic information

Product Name:
L-(-)-VESAMICOL HYDROCHLORIDE
Synonyms:
  • L-(-)-VESAMICOL HYDROCHLORIDE
  • 1r-trans-cyclohexano
  • L(-)-VESAMICOL HCL
  • L-(-)-2-(4-Phenylpiperidino)cyclohexanol hydrochloride
  • (1R,2R)-2-(4-phenylpiperidin-1-yl)cyclohexan-1-ol
  • Cyclohexanol, 2-(4-phenyl-1-piperidinyl)-, (1R,2R)-
CAS:
112709-59-8
MF:
C17H25NO
MW:
259.39
Mol File:
112709-59-8.mol
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L-(-)-VESAMICOL HYDROCHLORIDE Chemical Properties

Melting point:
238.5-240.0 °C
Boiling point:
393.5±42.0 °C(Predicted)
Density 
1.086±0.06 g/cm3(Predicted)
pka
15.16±0.40(Predicted)
form 
solid
color 
white
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Safety Information

Safety Statements 
22-24/25
WGK Germany 
3
RTECS 
GW0765050

MSDS

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L-(-)-VESAMICOL HYDROCHLORIDE Usage And Synthesis

Uses

(-)-Vesamicol (AH5183) is an inhibitor of acetylcholine transport into synaptic vesicles, with the IC50 of 75 nM[1]. (-)-Vesamicol can be used for release and recycling of synaptic vesicles study[1].

Definition

ChEBI: (1R,2R)-2-(4-phenyl-1-piperidinyl)-1-cyclohexanol is a member of piperidines.

References

[1] Searl T, et al. Acetylcholine recycling and release at rat motor nerve terminals studied using (-)-vesamicol and troxpyrrolium. J Physiol. 1991;444:99-116. DOI:10.1113/jphysiol.1991.sp018868

L-(-)-VESAMICOL HYDROCHLORIDESupplier

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