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17-PHENYL TRINOR PROSTAGLANDIN E2

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17-PHENYL TRINOR PROSTAGLANDIN E2 Basic information

Product Name:
17-PHENYL TRINOR PROSTAGLANDIN E2
Synonyms:
  • 17-PHENYL-TRINOR-PROSTAGLANDIN E2 98%
  • 17-PHENYL TRINOR PROSTAGLANDIN E2 99+%
  • 17-Phenyl-18,19,20-trinor-PGE2
  • 17-Phenyl-18,19,20-trinorprostaglandin E2
  • 17-Phenyl-omega-trinor-PGE2
  • 17-PHENYL TRINOR PROSTAGLANDIN E2
  • 9-OXO-11ALPHA-15S-DIHYDROXY-17-PHENYL-18,19,20-TRINOR-PROSTA-5Z,13E-DIEN-1-OIC ACID
  • 17-Phenyltrinorprostaglandinee2
CAS:
38315-43-4
MF:
C23H30O5
MW:
386.48
Mol File:
38315-43-4.mol
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17-PHENYL TRINOR PROSTAGLANDIN E2 Chemical Properties

Boiling point:
597.1±50.0 °C(Predicted)
Density 
1?+-.0.06 g/cm3(Predicted)
RTECS 
MJ9681060
solubility 
DMF: >100 mg/ml (from Fluprostenol); DMSO: >100 mg/ml (from Fluprostenol); Ethanol: >100 mg/ml (from Fluprostenol); PBS pH 7.2: >0.8 mg/ml (from 17-phenyl tri
pka
4.75±0.10(Predicted)
form 
Oil
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17-PHENYL TRINOR PROSTAGLANDIN E2 Usage And Synthesis

Uses

17-Phenyl-trinor-prostaglandin E2 is a synthetic analog of PGE2 and an agonist at the EP1 and EP3 receptor (1). Prostaglandin E2(PGE2) regulates neuroinflammatory responses and is upregulated in brain injury by cyclooxygenase 2 (COX-?2) and membrane-bound PGE synthase. 17-Phenyl-trinor-prostaglandin E2 can be used to investigate inflammatory signaling pathways (2).

Definition

ChEBI: 17-phenyl-18,19,20-trinor-prostaglandin E2 is a prostanoid that is 18,19,20-trinor-prostaglandin E2 in which one of the terminal methyl hydrogens has been replaced by a phenyl group. It has a role as a human metabolite and a prostaglandin receptor agonist. It is a prostanoid, an alicyclic ketone, a beta-hydroxy ketone, a secondary alcohol, an oxo monocarboxylic acid, a hydroxy monocarboxylic acid and an olefinic compound.

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