6-Carboxytetramethylrhodamine succinimidyl ester Chemical Properties

storage temp. 

−20°C

solubility 

DMF: soluble

form 

Solid

color 

Dark purple to black

Appearance

Purple solid

ex/em

550/576 nm (MeOH/PBS)

ε(extinction coefficient)

90000 L⋅mol−1⋅cm−1

Φ(quantum yield)

0.1

InChIKey

PAOQTZWNYMMSEE-UHFFFAOYSA-N

SMILES

C(C1C=CC(=CC=1C1=C2C=CC(=CC2=[O+]C2C=C(C=CC1=2)N(C)C)N(C)C)C(=O)ON1C(CCC1=O)=O)(=O)[O-]

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-36

WGK Germany 

3

F 

8-10-21

6-Carboxytetramethylrhodamine succinimidyl ester Usage And Synthesis

Description

TAMRA (tetramethylrhodamine) is a xanthene dye with a fluorescence maximum at 567 nm.

This product is an N-Hydroxysuccinimide (NHS)-ester of TAMRA dye. Pure 6-isomer. TAMRA NHS-ester readily reacts with various amines and is used to generate fluorescently labeled proteins, peptides, antibodies, and other biomolecules.

Chemical Properties

Appearance: Purple solid
ex/em: 550/576 nm (MeOH/PBS)
Extinction coefficient (ε): 90000 L??mol??1??cm??1
Quantum yield (Φ): 0.1

Uses

6-TAMRA SE is a fluorescent indicator.

Uses

Amine-reactive form of 6-Carboxytetramethylrhodamine succinimidyl ester used for labeling of peptides and aminoglycoside antibiotics. It is also most commonly used in automated DNA sequencing.

Abs/Em Maxima

541/567 nm

Fluoresene quantum yield

0.1

Extinction Coefficient

84000

CF260

0.34

CF280

0.17

6-Carboxytetramethylrhodamine succinimidyl ester(150810-69-8)Related Product Information

• Maleimide
• 5-CARBOXYTETRAMETHYLRHODAMINE
• Olibanum oil
• O-Phthalimide
• Tris(trimethylsilyl)phosphate
• BUTYL OLEATE
• Methyl acrylate
• Dimethyl succinate
• Bismaleimide
• Succinimide
• 1,4-DIISOCYANATOBUTANE
• 6-Carboxytetramethylrhodamine
• 5(6)-Carboxytetramethylrhodamine N-succinimidyl ester
• DIALIFOS
• RHODAMINE 110
• 6-TAMRA
• SUCCINIMIDYL 4-FORMYLBENZOATE
• 5-CARBOXY-TETRAMETHYLRHODAMINE N-SUCCINIMIDYL ESTER