8-Methylquinoline Chemical Properties

Melting point:

-80 °C

Boiling point:

245 °C

Density 

1.052 g/mL at 25 °C(lit.)

refractive index 

n20/D 1.614(lit.)

Flash point:

221 °F

storage temp. 

Room Temperature

solubility 

Chloroform, Methanol

pka

5.03±0.17(Predicted)

form 

Liquid

color 

Clear yellow

Specific Gravity

1.052

Water Solubility 

0.1-0.5 g/100 mL at 17 ºC

BRN 

111340

InChIKey

JRLTTZUODKEYDH-UHFFFAOYSA-N

CAS DataBase Reference

611-32-5(CAS DataBase Reference)

NIST Chemistry Reference

Quinoline, 8-methyl-(611-32-5)

EPA Substance Registry System

8-Methylquinoline (611-32-5)

Safety Information

Hazard Codes 

Xi,Xn

Risk Statements 

36/37/38-68-22

Safety Statements 

26-36-45-36/37/39

WGK Germany 

3

RTECS 

VC0562000

TSCA 

T

HazardClass 

IRRITANT

HS Code 

29334900

MSDS

• Language:English Provider:8-Methylquinoline
• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS
• Language:English Provider:ALFA

8-Methylquinoline Usage And Synthesis

Chemical Properties

clear yellow liquid

Uses

8-Methylquinoline has been used in preparation of osmium chloridophosphine complexes, as quinoline carbene tautomers.Tumorigenic potential of 8-methylquinoline has been evaluated in newborn CD-1 mice and Sprague-Dawley rats.

Uses

8-Methylquinoline is used in QSAR treatment of mutagenicity and cytotoxicity of quinolines.

Definition

ChEBI: A methylquinoline carrying a methyl substituent at position 8.

Synthesis Reference(s)

The Journal of Organic Chemistry, 45, p. 1514, 1980 DOI: 10.1021/jo01296a035

General Description

Yellow liquid or oil.

Air & Water Reactions

Slightly soluble in water.

Reactivity Profile

8-Methylquinoline may be sensitive to exposure to light. May react vigorously with strong oxidizing agents and strong acids . Neutralizes acids in exothermic reactions to form salts plus water. May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen may be generated in combination with strong reducing agents, such as hydrides.

Fire Hazard

8-Methylquinoline is combustible.

Purification Methods

Purify it as for 2-methylquinoline. The phosphate and picrate have m 158o and m 201o, respectively. [Beilstein 20 III/IV 3500, 20/7 V 405.]

8-Methylquinoline(611-32-5)Related Product Information

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