HUMAN IL-8 Chemical Properties

Boiling point:

715.1±60.0 °C(Predicted)

Density 

1.391±0.06 g/cm3(Predicted)

storage temp. 

−20°C

form 

lyophilized powder

pka

2.60±0.10(Predicted)

biological source

human

Safety Information

Safety Statements 

22-24/25

WGK Germany 

3

HS Code 

3504009000

MSDS

• Language:English Provider:SigmaAldrich

HUMAN IL-8 Usage And Synthesis

Uses

Interleukin-8 (IL-8) human has ben used to:

• measure neutrophil chemotoxis
• study the uptake of apoptotic cells by meningothelial cells
• study the effect of IL-8 on expression and secretion of urocortin-1 by human umbilical vein endothelial cells

Biochem/physiol Actions

Interleukin-8 (IL-8) was formerly called monocyte-derived neutrophil chemotactic factor. It belongs to the chemokine α or C-X-C family. Like other members of this family, the mature form of IL-8 has four cysteine residues and the first two cysteine residues are separated by glutamine. IL-8 shows chemotactic activity in vitro for T cells, neutrophils and basophils. Mutation in IL-8 can increase risk to acute pancreatitis.

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