CYCLOPENTYL PHENYL KETONE Chemical Properties

Boiling point:

136-140°C 16mm

Density 

1,036 g/cm³

refractive index 

1.5440

Flash point:

>110°C

storage temp. 

Sealed in dry,Room Temperature

solubility 

Chloroform, Methanol (Slightly)

form 

Oil

color 

Pale Yellow

Specific Gravity

1.04

BRN 

2045903

InChIKey

VYDIMQRLNMMJBW-UHFFFAOYSA-N

CAS DataBase Reference

5422-88-8(CAS DataBase Reference)

EPA Substance Registry System

Methanone, cyclopentylphenyl- (5422-88-8)

Safety Information

Safety Statements 

23-24/25

TSCA 

Yes

HS Code 

2914.39.9000

MSDS

• Language:English Provider:ALFA

CYCLOPENTYL PHENYL KETONE Usage And Synthesis

Description

Phenyl cyclopentyl ketone (Item No. 31036) is an analytical reference standard categorized as a precursor in the synthesis of ketamine (Item Nos. 19389 | 11630). This product is intended for research and forensic applications.

Uses

Phenylcyclopentyl ketone is the key intermediate of synthetic hydrochloric acid amyl ethyl quin ether.

Uses

Cyclopentyl Phenyl Ketone is used in the preparation of ortho-arylated compounds and phenanthrones by palladium-catalyzed chelation-assisted C-H activation of Cyclopentyl Phenyl Ketone.

Synthesis

In 100ml round-bottomed flask, by 2-cyclopenta ethyl benzoylacetate (10.6g, 43.05mmol, 1.0eq), NaOH (2.6g, 64.5mmol) and Na2CO3(4.5g, 43mmol), is suspended in 50.0mLH2In O, it is warmed up to 80 DEG C and reacts 3 hours, obtain product phenylcyclopentyl ketone.Purify: reactant liquor is cooled to room temperature, extract 3 times with ethyl acetate 20mL；Organic phase saturated sodium-chloride washs, and merges organic phase and uses anhydrous MgSO4Being dried, then remove solvent under reduced pressure, obtain thick product, column chromatography purifies, and eluant, eluent is ethyl acetate: petroleum ether (1:10), obtains 6.54g target product, yield 87.2%.

CYCLOPENTYL PHENYL KETONE(5422-88-8)Related Product Information

• CYCLOPENTYL BENZOATE
• 1-cyclopentyl-1-phenylethane-1,2-diol
• 2-cyclopentyl-2-phenyloxirane
• Penehyclidine Impurity 18
• Benzoylformic acid
• LPHE-009
• alpha-Cyclopentylmandelic acid
• glycopyrronium bromide
• Methyl (R)-(-)-cyclopentylmandelate
• (S)-1-methylpyrrolidin-3-yl (R)-2-cyclopentyl-2-hydroxy-2-phenylacetate
• Methyl cyclopentylphenylglycolate
• 2-cyclopentylidene-2-phenylacetic acid
• Glycopyrrolate Impurity (1,1-Dimethyl-3-Hydroxy-pyrrolidinium Bromide)
• (R)-(R)-1-methylpyrrolidin-3-yl 2-cyclopentyl-2-hydroxy-2-phenylacetate(WXC03446)
• (R)-(-)-1-Methyl-3-pyrrolidinol
• 1-methylpyrrolidin-3-yl cyclopentylphenylglycolate
• threo-Glycopyrronium bromide
• Glycopyrrolate Erythro Isomer