Basic information Safety Supplier Related
ChemicalBook >  Product Catalog >  Biochemical Engineering >  nucleic acid drugs >  N-Benzoyl-2'-deoxy-adenosine

N-Benzoyl-2'-deoxy-adenosine

Basic information Safety Supplier Related

N-Benzoyl-2'-deoxy-adenosine Basic information

Product Name:
N-Benzoyl-2'-deoxy-adenosine
Synonyms:
  • N-[9-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)-2-oxolanyl]-6-purinyl]benzamide
  • DA-BZ
  • N6-BZ-2'-DEOXYADENOSINE
  • N6-BENZOYLDEOXYADENOSINE
  • N-BZ-DA
  • n-benzoyl-2'-deoxy-adenosine
  • n-benzoyl-2’-deoxy-adenosin
  • BZ-DEOXYADENOSINE
CAS:
4546-72-9
MF:
C17H17N5O4
MW:
355.35
EINECS:
224-903-6
Product Categories:
  • Nucleic acids
  • Modified(deoxy)nucleoside
Mol File:
4546-72-9.mol
More
Less

N-Benzoyl-2'-deoxy-adenosine Chemical Properties

Melting point:
120-122C
Density 
1.61±0.1 g/cm3(Predicted)
storage temp. 
Sealed in dry,Store in freezer, under -20°C
solubility 
DMF: 30 mg/ml; DMF:PBS (pH 7.2) (1:6): 0.14 mg/ml; DMSO: 15 mg/ml; Ethanol: 1 mg/ml
form 
A crystalline solid
pka
7.87±0.43(Predicted)
Water Solubility 
Soluble in water (slightly), and methanol (20 mg/ml).
CAS DataBase Reference
4546-72-9(CAS DataBase Reference)
More
Less

Safety Information

Safety Statements 
24/25
HS Code 
29349990
More
Less

N-Benzoyl-2'-deoxy-adenosine Usage And Synthesis

Description

N-Benzoyl-2'-deoxyadenosine is a nucleoside analog that is used in the diagnosis of infections caused by bacteria. N-Benzoyl-2'-deoxyadenosine binds to DNA duplexes and alters their structure, which can be detected using electrophoresis. N-Benzoyl-2'-deoxyadenosine has been shown to have low bioavailability and is insoluble in water, so it must be administered intravenously. It has also been found to have anti-inflammatory properties, which may be due to its ability to inhibit prostaglandin synthesis.

Uses

Reactant in the synthesis of 2', 5'-Dideoxycytidines and Other Derivatives of 2'-Deoxycytidine. Reactant in the synthesis of Mono- and Diamino Analogues of 2?-Deoxyadenosine, Cordycepin, 9-(3-Deoxy-α-D-Threo-Pentofuranosyl)-Adenine and 9-(2-Deoxy-α-D-Threo-Pentofuranosyl)Adenine.

N-Benzoyl-2'-deoxy-adenosineSupplier

Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
021-61259108 18621169109
Email
market03@meryer.com
Hongene Biotech Corporation
Tel
021-64757213
Email
info@hongene.com
Alfa Aesar
Tel
400-6106006
Email
saleschina@alfa-asia.com
Jia Xing Isenchem Co.,Ltd
Tel
0573-85285100 18627885956
Email
isenchem@163.com
Wuhu Huaren Science and Technology Co., Ltd.
Tel
0553-0553-0553-5842013-801-801 18155347026
Email
jinhuaren@huarensh.com