N-Benzoyl-2'-deoxy-adenosine
N-Benzoyl-2'-deoxy-adenosine Basic information
- Product Name:
- N-Benzoyl-2'-deoxy-adenosine
- Synonyms:
-
- N-[9-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)-2-oxolanyl]-6-purinyl]benzamide
- DA-BZ
- N6-BZ-2'-DEOXYADENOSINE
- N6-BENZOYLDEOXYADENOSINE
- N-BZ-DA
- n-benzoyl-2'-deoxy-adenosine
- n-benzoyl-2’-deoxy-adenosin
- BZ-DEOXYADENOSINE
- CAS:
- 4546-72-9
- MF:
- C17H17N5O4
- MW:
- 355.35
- EINECS:
- 224-903-6
- Product Categories:
-
- Nucleic acids
- Modified(deoxy)nucleoside
- Mol File:
- 4546-72-9.mol
N-Benzoyl-2'-deoxy-adenosine Chemical Properties
- Melting point:
- 120-122C
- Density
- 1.61±0.1 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Store in freezer, under -20°C
- solubility
- DMF: 30 mg/ml; DMF:PBS (pH 7.2) (1:6): 0.14 mg/ml; DMSO: 15 mg/ml; Ethanol: 1 mg/ml
- form
- A crystalline solid
- pka
- 7.87±0.43(Predicted)
- Water Solubility
- Soluble in water (slightly), and methanol (20 mg/ml).
- CAS DataBase Reference
- 4546-72-9(CAS DataBase Reference)
Safety Information
- Safety Statements
- 24/25
- HS Code
- 29349990
N-Benzoyl-2'-deoxy-adenosine Usage And Synthesis
Description
N-Benzoyl-2'-deoxyadenosine is a nucleoside analog that is used in the diagnosis of infections caused by bacteria. N-Benzoyl-2'-deoxyadenosine binds to DNA duplexes and alters their structure, which can be detected using electrophoresis. N-Benzoyl-2'-deoxyadenosine has been shown to have low bioavailability and is insoluble in water, so it must be administered intravenously. It has also been found to have anti-inflammatory properties, which may be due to its ability to inhibit prostaglandin synthesis.
Uses
Reactant in the synthesis of 2', 5'-Dideoxycytidines and Other Derivatives of 2'-Deoxycytidine. Reactant in the synthesis of Mono- and Diamino Analogues of 2?-Deoxyadenosine, Cordycepin, 9-(3-Deoxy-α-D-Threo-Pentofuranosyl)-Adenine and 9-(2-Deoxy-α-D-Threo-Pentofuranosyl)Adenine.
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N-Benzoyl-2'-deoxy-adenosine(4546-72-9)Related Product Information
- Benzoyl chloride
- Adenosine
- 5'-Deoxyadenosylcobalamin
- Sodium benzoate
- 2'-Deoxyadenosine
- Difenoconazole
- Chlorantraniliprole
- Sodium lauroylglutamate
- Benzoyl peroxide
- ADENOSINE 5'-TRIPHOSPHATASE
- 2'-Deoxyadenosine monohydrate
- N-Benzoyl-2'-deoxy-cytidine
- 2-Amino-6-chloropurine-9-riboside
- IBU-DEOXYCYTIDINE
- 6-Chloropurine riboside
- DMT-dA(bz) Phosphoramidite
- N6-Benzoyl-2'-deoxyadenosine
- N-Benzoyl-2'-deoxy-adenosine