Glycidyl phenyl ether
- Product Name:
- Glycidyl phenyl ether
- Product Categories:
- Simple 3-Membered Ring Compounds
- Mol File:
Glycidyl phenyl ether Chemical Properties
- Melting point:
- 3.5 °C(lit.)
- Boiling point:
- 245-247 °C(lit.)
- 1.109 g/mL at 25 °C(lit.)
- vapor density
- 5.2 (vs air)
- vapor pressure
- 0.03 mm Hg ( 20 °C)
- refractive index
- n20/D 1.531
- Flash point:
- >230 °F
- storage temp.
- Store below +30°C.
- Clear colorless to yellow
- Water Solubility
- 2.4 g/L (20 ºC)
- Exposure limits
- TLV-TWA 6 mg/m3 (1 ppm) (ACGIH); 1 ppm (15 min) (NIOSH).
- Stable. Incompatible with strong oxidizing agents.
- CAS DataBase Reference
- 122-60-1(CAS DataBase Reference)
- NIST Chemistry Reference
- Oxirane, (phenoxymethyl)-(122-60-1)
- EPA Substance Registry System
- Oxirane, (phenoxymethyl)-(122-60-1)
- Hazard Codes
- Risk Statements
- Safety Statements
- WGK Germany
- Autoignition Temperature
- 430 °C
- HS Code
- Hazardous Substances Data
- 122-60-1(Hazardous Substances Data)
- LD50 orally in Rabbit: 2150 mg/kg LD50 dermal Rabbit 1500 mg/kg
Glycidyl phenyl ether Usage And Synthesis
Phenyl glycidyl ether is a colorless liquid with an unpleasant sweet odor
Phenyl glycidyl ether (PGE) is used as anintermediate in organic syntheses.
Air & Water Reactions
Ethers tend to form unstable peroxides when exposed to oxygen. Ethyl, isobutyl, ethyl tert-butyl, and ethyl tert-pentyl ether are particularly hazardous in this respect. Ether peroxides can sometimes be observed as clear crystals deposited on containers or along the surface of the liquid. Slightly soluble in water.
Glycidyl phenyl ether, an ether, can act as a base. They form salts with strong acids and addition complexes with Lewis acids. The complex between diethyl ether and boron trifluoride is an example. Ethers may react violently with strong oxidizing agents. In other reactions, which typically involve the breaking of the carbon-oxygen bond, ethers are relatively inert.
PGE is a toxic compound exhibiting moderate irritant action and carcinogenicity inanimals. Application of 0.25 mg resulted insevere eye irritation in rabbits, while 500 mgcaused moderate skin irritation over a periodof 24 hours. Prolonged or repeated contactcan cause moderate irritation and skin sensitization in humans.
The symptoms of its toxicity in animalswere depression of the central nervous system and paralysis of the respiratory tract.Prolonged exposure caused changes in thekidney, liver, thymus, and testes, and lossof hair in rats. The toxicity of this compound in humans is low and the health hazardcan arise primarily from its skin-sensitizationaction.
LD50 value, oral (mice): 1400 mg/kg
DGE showed carcinogenicity in rats, causingnasal cancer.
Glycidyl phenyl ether is probably combustible.
This monoglycidyl derivative is a reactive diluent in epoxy resins Bisphenol A type. It is a component of epoxy paints, epoxy glues, and epoxy resins. Sensitization has been observed in many professions, such as in construction workers, marble workers, ceramic workers, and shoemakers.
Confirmed carcinogen with experimental carcinogenic data. Moderately toxic by ingestion, skin contact, and subcutaneous routes. A severe eye and skin irritant. Experimental reproductive effects. Mutation data reported. When heated to decomposition it emits acrid smoke and irritating fumes. Used as a chemical intermediate. See also ETHERS
PGE is used to increase storage time and stability of halogenated compounds; as a reactive diluent in uncured epoxy resins to reduce the viscosity of the uncured system for ease in casting; adhesive, and laminating applications. NIOSH once estimated that 8000 workers are potentially exposed to PGE.
UN2810 Toxic liquids, organic, n.o.s., Hazard Class: 6.1; Labels: 6.1-Poisonous materials, Technical Name Required.
Incompatible with oxidizers (chlorates, nitrates, peroxides, permanganates, perchlorates, chlorine, bromine, fluorine, etc.); contact may cause fires or explosions. Keep away from alkaline materials, strong bases, strong acids, oxoacids, epoxides, amines, and curing agents. PGE can presumably form explosive peroxides
Concentrated waste containing no peroxides-discharge liquid at a controlled rate near a pilot flame. Concentrated waste containing peroxidesperforation of a container of the waste from a safe distance followed by open burning.
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- Butyl glycidyl ether
- GLYCIDYL ACRYLATE
- BENZYL GLYCIDYL ETHER
- Styrene oxide
- Diethyl ether
- ISOPROPYLPHENYLDIPHENYL PHOSPHATE
- Phenyl salicylate
- Propylene oxide
- DIGLYCIDYL ETHER
- Ethylene glycol diglycidyl ether
- Diphenyl ether
- 1,2,3-PROPANETRIOL GLYCIDYL ETHER
- Dimethyl ether
- BISPHENOL A DIGLYCIDYL ETHER RESIN