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(-)-GALLOCATECHIN

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(-)-GALLOCATECHIN Basic information

Product Name:
(-)-GALLOCATECHIN
Synonyms:
  • [2S,3R]-2-[3,4,5-TRIHYDROXYPHENYL]-3,4-DIHYDRO-1[2H]-BENZOPYRAN-3,5,7-TRIOL
  • (-)-GALLOCATECHIN
  • GALLOCATECHIN
  • (-)-GC
  • ()-Gallocatechin,(2S,3R)-2-(3,4,5-Trihydroxyphenyl)-3,4-dihydro-1(2H)-benzopyran-3,5,7-triol
  • (2S,3R)-3,4-dihydro-2-(3,4,5-trihydroxyphenyl)-2H-1-benzopyran-3,5,7-triol
  • (2S-trans)-3,4-Dihydro-2-(3,4,5-trihydroxyphenyl)-2H-1-benzopyran-3,5,7-triol
  • l-Gallocatechin
CAS:
3371-27-5
MF:
C15H14O7
MW:
306.27
Product Categories:
  • phytochemical
  • reference standards from Chinese medicinal herbs (TCM).
  • Aromatics
  • chemical reagent
  • pharmaceutical intermediate
  • standardized herbal extract
  • Miscellaneous Natural Products
  • Catechins & Tannins
  • Heterocycles
  • Inhibitors
Mol File:
3371-27-5.mol
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(-)-GALLOCATECHIN Chemical Properties

Melting point:
200℃
Boiling point:
685.6±55.0 °C(Predicted)
Density 
1.695±0.06 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
H2O: 5 mg/mL with brief sonication
form 
Solid
pka
9.02±0.15(Predicted)
color 
Pale Grey
InChIKey
XMOCLSLCDHWDHP-DOMZBBRYSA-N
LogP
-0.100 (est)
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Safety Information

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
WGK Germany 
3
HS Code 
29339900

MSDS

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(-)-GALLOCATECHIN Usage And Synthesis

Chemical Properties

Off-White Solid

Uses

An antioxidant with free radical scavenging ability; a potential cancer chemopreventive agent. It inhibits the growth and adherence of P. gingivalis onto the buccal epithelial cells. An epimer of (-)- Epigallocatechin (E588940).

Uses

Polyphenolic compound from green tea. Possesses free-radical scavenging ability

Uses

(?)-Gallocatechin has been used as a reference standard:

  • for the identification of phenolic compounds present in Pineapple (Ananas comosus) using high-performance liquid chromatography (HPLC)
  • to evaluate the catechin profiles from Camellia sinensis green tea, white tea, and flower sample by high-performance liquid chromatography/photodiode array detection (RP-HPLC/PDAD) analysis
  • as a reference standard for the flavan-3-ols profiling muscadine grape hybrid varieties using high-performance liquid chromatography-quadrupole, time-of-flight, tandem mass spectrometry (HPLC-qTOF-MS/MS) analysis

Definition

ChEBI: (-)-gallocatechin is a a gallocatechin that has (2S,3R)-configuration. It has a role as an antioxidant, a radical scavenger and a metabolite. It is an enantiomer of a (+)-gallocatechin.

General Description

Gallocatechin belongs to the catechin class of organic compounds and is one of the major components of green tea. The beneficial effects of catechins include anti-tumorigenic, anti-mutagenic, anti-pathogenic, and anti-oxidative properties.

Biochem/physiol Actions

(?)-Gallocatechin (GC) exerts antioxidant properties by scavenging free radicals. It can also inhibit osteoclastgenesis. GC elicits antimutagenic activity in Escherichia coli against ultraviolet (UV)-induced mutation. It also displays an inhibitory effect on the growth and adherence of?Porphyromonas gingivalis?in the buccal epithelial cells.

target

ROS

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