3,4-DIHYDROXYBENZYLAMINE HYDROBROMIDE CAS#: 16290-26-9

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3,4-DIHYDROXYBENZYLAMINE HYDROBROMIDE

Basic information Safety Supplier Related

3,4-DIHYDROXYBENZYLAMINE HYDROBROMIDE Basic information

Product Name:

3,4-DIHYDROXYBENZYLAMINE HYDROBROMIDE

Synonyms:

4-(AMINOMETHYL)CATECHOL HYDROBROMIDE
3,4-DIHYDROXYBENZYLAMINE HYDROBROMIDE
DHBA
DHBA HYDROBROMIDE
4-(aminomethyl)pyrocatechol hydrobromide
3,4-DIHYDROXYBENZYLAMINE HYDROBROMIDE, 9 8%
4-(Aminomethyl)catechol hydrobromide, DHBA hydrobromide
3,4-Dihydroxybenzylamine·hydrogen bromide

CAS:

16290-26-9

MF:

C7H10BrNO2

MW:

220.06

EINECS:

240-382-8

Product Categories:

Anilines, Aromatic Amines and Nitro Compounds

Mol File:

16290-26-9.mol

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3,4-DIHYDROXYBENZYLAMINE HYDROBROMIDE Chemical Properties

Melting point:: 184-186 °C(lit.)
storage temp.: Inert atmosphere,Room Temperature
solubility: DMSO (Slightly), Methanol (Very Slightly)
form: Crystalline Powder
color: Light beige
Sensitive: Hygroscopic
BRN: 4002646
InChI: 1S/C7H9NO2.BrH/c8-4-5-1-2-6(9)7(10)3-5;/h1-3,9-10H,4,8H2;1H
InChIKey: BVFZTXFCZAXSHN-UHFFFAOYSA-N
SMILES: Br.NCc1ccc(O)c(O)c1
CAS DataBase Reference: 16290-26-9(CAS DataBase Reference)

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Safety Information

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-36
WGK Germany: 3
F: 10
HS Code: 29222900
Storage Class: 11 - Combustible Solids
Hazard Classifications: Eye Irrit. 2
Skin Irrit. 2
STOT SE 3

MSDS

Language:English Provider:ACROS
Language:English Provider:SigmaAldrich
Language:English Provider:ALFA

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3,4-DIHYDROXYBENZYLAMINE HYDROBROMIDE Usage And Synthesis

Chemical Properties

light beige crystalline powder

Uses

4-(Aminomethyl)benzene-1,2-diol hydrobromide is a useful reactant for the synthesis of capsaicin soft drugs. which are used to target the transient receptor potential vanilloid 1 channel (TRPV1).

in vivo

3,4-Dihydroxybenzylamine hydrobromide (intraperitoneal injection; 1000 mg/kg; 7 days) has the least toxic effect in non-tumor-bearing B6D2F1 mice,and mice is tolerated at this dose^[3]. 3,4-Dihydroxybenzylamine hydrobromide (intraperitoneal injection; 200-800 mg/kg; 21 days) has different effects at different doses, the median life-span are 17, 24.5, 26, 29 and 25 days for 0 mg/kg, 200 mg/kg, 400 mg/kg, 600 mg/kg, and 800 mg/kg, respectively^[3].

Animal Model:	C57BL/6 mice with B6D2F1 cells^[3]
Dosage:	200 mg/kg, 400 mg/kg, 600 mg/kg, and 800 mg/kg
Administration:	Intraperitoneal injection
Result:	Exhibited increased life-span of 44%,46%, 70% and 50% for 200 mg/kg, 400 mg/kg, 600 mg/kg, and 800 mg/kg, respectively.

3,4-DIHYDROXYBENZYLAMINE HYDROBROMIDESupplier

J & K SCIENTIFIC LTD.

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3B Pharmachem (Wuhan) International Co.,Ltd.

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Alfa Aesar

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