Basic information Safety Supplier Related
ChemicalBook >  Product Catalog >  Organic Chemistry >  Amides >  Acyclic polyamines and their derivatives >  N,N,N',N'-Tetramethylethylenediamine

N,N,N',N'-Tetramethylethylenediamine

Basic information Safety Supplier Related

N,N,N',N'-Tetramethylethylenediamine Basic information

Product Name:
N,N,N',N'-Tetramethylethylenediamine
Synonyms:
  • N1,N1,N2,N2-tetraMethylethane-1,2-diaMine
  • N,N,N',N'-Tetramethylethane-1,2-diamine, electrophoresis grade
  • 1,2-EthanediaMine,N1,N1,N2,N2-tetraMethyl-
  • Four MethylEthylenediaMine
  • N,N,N',N'-TetraMethylethylenediaMine >=99.5%, purified by redistillation
  • N,N,N',N'-TetraMethylethylenediaMine ReagentPlus(R), 99%
  • (CH3)2NCH2CH2N(CH3)2
  • 1,2-Diaminoethane, N,N,N',N'-tetramethyl-
CAS:
110-18-9
MF:
C6H16N2
MW:
116.2
EINECS:
203-744-6
Product Categories:
  • Intermediates
  • Biochemistry
  • Reagents for Electrophoresis
  • Aliphatics
  • Amines
  • Pyridines
  • bc0001
Mol File:
110-18-9.mol
More
Less

N,N,N',N'-Tetramethylethylenediamine Chemical Properties

Melting point:
−55 °C(lit.)
Boiling point:
120-122 °C(lit.)
Density 
0.775 g/mL at 20 °C(lit.)
vapor density 
4 (vs air)
vapor pressure 
21 hPa (20 °C)
refractive index 
n20/D 1.4179(lit.)
Flash point:
50 °F
storage temp. 
Store below +30°C.
solubility 
H2O: 10 mg/mL at 20 °C, clear, colorless
form 
Liquid
pka
10.40, 8.26(at 25℃)
Specific Gravity
0.777 (20/4℃)
color 
Clear colorless to slightly yellow
Odor
Amine like
PH
8.0-8.5 (0.1g/l, H2O, 20℃)
explosive limit
1-9%(V)
Water Solubility 
miscible
Sensitive 
Hygroscopic
Merck 
14,9134
BRN 
1732991
Stability:
Stable. Highly flammable. Incompatible with strong oxidizing agents, acids, acid chlorides, acid anhydrides, copper, mercury.
InChIKey
DMQSHEKGGUOYJS-UHFFFAOYSA-N
LogP
-0.13 at 20.2℃
CAS DataBase Reference
110-18-9(CAS DataBase Reference)
NIST Chemistry Reference
1,2-Ethanediamine, N,N,N',N'-tetramethyl-(110-18-9)
EPA Substance Registry System
Tetramethylethylenediamine (110-18-9)
More
Less

Safety Information

Hazard Codes 
F,C,Xi
Risk Statements 
11-20/22-34-20/21/22
Safety Statements 
16-26-36/37/39-45
RIDADR 
UN 2372 3/PG 2
WGK Germany 
1
RTECS 
KV7175000
3-8-10-34
Autoignition Temperature
145 °C
Hazard Note 
Irritant
TSCA 
Yes
HazardClass 
3
PackingGroup 
II
HS Code 
29212900
Hazardous Substances Data
110-18-9(Hazardous Substances Data)

MSDS

  • Language:English Provider:TEMED
  • Language:English Provider:ACROS
  • Language:English Provider:SigmaAldrich
  • Language:English Provider:ALFA
More
Less

N,N,N',N'-Tetramethylethylenediamine Usage And Synthesis

Chemical Properties

Colorless to slightly yellow liquid

Uses

N,N,N',N'-Tetramethylethylenediamine is used as polymerization accelerator in gel electrophoresis, solvent and oxidizing reagent. It is also used for the separation of proteins or nucleic acids. Further, it is employed as a ligand for metal ions like zinc and copper. It is actively involved in the formation of anionic organometallic complex.

Definition

ChEBI: N,N,N',N'-tetramethylethylenediamine is an ethylenediamine derivative in which each nitrogen carries two methyl substituents. It is widely employed both as a ligand for metal ions and as a catalyst in organic polymerisation. It has a role as a chelator and a catalyst.

General Description

1,2-di-(dimethylamino)ethane appears as a water-white colored liquid with a fishlike odor. Flash point 68 °F. Less dense than water. Vapors heavier than air. Used to make other chemicals.

Air & Water Reactions

Highly flammable. Slightly soluble in water. Sensitive to heat and may be sensitive to air .

Reactivity Profile

N,N,N',N'-Tetramethylethylenediamine neutralizes acids in exothermic reactions to form salts plus water. May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen may be generated in combination with strong reducing agents, such as hydrides.

Health Hazard

May cause toxic effects if inhaled or absorbed through skin. Inhalation or contact with material may irritate or burn skin and eyes. Fire will produce irritating, corrosive and/or toxic gases. Vapors may cause dizziness or suffocation. Runoff from fire control or dilution water may cause pollution.

Fire Hazard

HIGHLY FLAMMABLE: Will be easily ignited by heat, sparks or flames. Vapors may form explosive mixtures with air. Vapors may travel to source of ignition and flash back. Most vapors are heavier than air. They will spread along ground and collect in low or confined areas (sewers, basements, tanks). Vapor explosion hazard indoors, outdoors or in sewers. Runoff to sewer may create fire or explosion hazard. Containers may explode when heated. Many liquids are lighter than water.

Safety Profile

Moderately toxic by ingestion. Mddly toxic by slun contact. A skin and severe eye irritant. Flammable when exposed to heat or flame; can react with oxidizing materials. When heated to decomposition it emits toxic fumes of NOx. See also MINES.

Purification Methods

Dry TMEDA partially with molecular sieves (Linde type 4A), then distil it in a vacuum from butyl lithium. This treatment removes all traces of primary and secondary amines and water. [Hay et al. J Chem Soc, Faraday Trans 1 68 1 1972.] Or dry it with KOH pellets, reflux for 2hours with one-sixth its weight of n-butyric anhydride (to remove primary and secondary amines) and fractionally distil it. Reflux it with fresh KOH, and distil it under nitrogen. [Cram & Wilson J Am Chem Soc 85 1245 1963.] It was also distilled from Na. Store it sealed under N2. The dipicrate has m 263o(dec). [Beilstein 4 H 250, 4 I 415, 4 II 690, 4 III 512, 4 IV 1172.]

N,N,N',N'-TetramethylethylenediamineSupplier

SHANGHAI BANGCHENG CHEMICAL Co.,Ltd. Gold
Tel
021-69106960 13701823733
Email
13701823733@163.com
Zhangjiagang hambadu chemical co. LTD Gold
Tel
0512-58923008 13862226968
Email
yf@halberdo.com
Shanghai Aladdin Bio-Chem Technology Co.,LTD Gold
Tel
400-400-6206333 18521732826
Email
market@aladdin-e.com
Shanghai Harvest Chemical Industrial Co., Ltd. Gold
Tel
21-31038972 15721252604
Email
ammyzuo@harvest-chem.com
Shanghai Xinyue Chemical Co., Ltd. Gold
Tel
18116267768
Email
645908973@qq.com