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ALKANNIN

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ALKANNIN Basic information

Product Name:
ALKANNIN
Synonyms:
  • (-)-(1-hydroxy-3-isohexenyl)naphthazarine
  • (-)-2-(1-hydroxy-4-methyl-3-pentenyl)-5,8-dihydroxy-1,4-naphthoquinone
  • (-)-5,8-dihydroxy-6-(1-hydroxy-4-methyl-3-pentenyl)-1,4-naphthalenedione
  • ANCHUSIN
  • ALKANNA TINCTORIA ROOT EXTRACT
  • ALKANET
  • NATURALRED20
  • ALKANNIN(P)
CAS:
23444-65-7
MF:
C16H16O5
MW:
288.3
Product Categories:
  • Anthraquinones, Hydroquinones and Quinones
Mol File:
23444-65-7.mol
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ALKANNIN Chemical Properties

Melting point:
149°C
Boiling point:
350.53°C (rough estimate)
Density 
1.1701 (rough estimate)
refractive index 
1.6200 (estimate)
pka
7.04±0.20(Predicted)
LogP
2.340 (est)
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Safety Information

Risk Statements 
22
Safety Statements 
22-24/25
Toxicity
mouse,LD50,oral,3gm/kg (3000mg/kg),Nahrung. Chemistry, Biochemistry, Microbiology, Technology, Nutrition. Vol. 15, Pg. 505, 1971.
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ALKANNIN Usage And Synthesis

Uses

Alkannin (cas# 23444-65-7) inhibits proliferation, migration and invasion of human Huh7 and Hep3B2.1-7 hepatocellular carcinoma cells via regulation of miR92a. It is also useful in the application of macromolecular crowding to investigate naphthoquinones shikonin, naphthazarin and related analogs for treatment of dermal scars in human.

Definition

ChEBI: Alkannin is a hydroxy-1,4-naphthoquinone.

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