ChemicalBook > Product Catalog > Chemical Reagents > Organic reagents > Sulfonyl halide > P-TOLUENESULFONYL FLUORIDE
P-TOLUENESULFONYL FLUORIDE
P-TOLUENESULFONYL FLUORIDE Basic information
- Product Name:
- P-TOLUENESULFONYL FLUORIDE
- Synonyms:
-
- 4-TOLUENESULPHONYL FLUORIDE
- 4-TOLUENESULFONYL FLUORIDE
- 4-METHYLBENZENESULFONYL FLUORIDE
- P-TOLUENESULFONYL FLUORIDE
- P-TOLUENESULPHONYL FLUORIDE
- TOSYL FLUORIDE
- 4-methyl-benzenesulfonylfluorid
- p-Fluorosulfonyltoluene
- CAS:
- 455-16-3
- MF:
- C7H7FO2S
- MW:
- 174.19
- EINECS:
- 207-238-6
- Product Categories:
-
- Organic Building Blocks
- Sulfonyl Halides
- Sulfur Compounds
- Mol File:
- 455-16-3.mol
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P-TOLUENESULFONYL FLUORIDE Chemical Properties
- Melting point:
- 41-42 °C(lit.)
- Boiling point:
- 112 °C16 mm Hg(lit.)
- Density
- 1.2768 (estimate)
- Flash point:
- 222 °F
- Water Solubility
- Hydrolyzes in water.
- Sensitive
- Moisture Sensitive
- BRN
- 2208423
- Exposure limits
- ACGIH: TWA 2.5 mg/m3
NIOSH: IDLH 250 mg/m3 - CAS DataBase Reference
- 455-16-3(CAS DataBase Reference)
- EPA Substance Registry System
- Benzenesulfonyl fluoride, 4-methyl- (455-16-3)
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Safety Information
- Hazard Codes
- C
- Risk Statements
- 20/21/22-34
- Safety Statements
- 22-26-27-36/37/39-45
- RIDADR
- UN 3261 8/PG 2
- WGK Germany
- 3
- RTECS
- XT8050000
- Hazard Note
- Corrosive
- TSCA
- T
- HazardClass
- 8
- PackingGroup
- II
- HS Code
- 29049095
- Toxicity
- rat,LD50,intraperitoneal,200mg/kg (200mg/kg),Nature. Vol. 173, Pg. 33, 1954.
MSDS
- Language:English Provider:SigmaAldrich
- Language:English Provider:ACROS
- Language:English Provider:ALFA
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P-TOLUENESULFONYL FLUORIDE Usage And Synthesis
Chemical Properties
White to beige fused mass
Uses
p-Toluenesulfonyl fluoride is used for sulfonylation of organometallic reagents as a simple, one-step synthesis of sulfones. It is useful in the treatment of Alzheimer?s disease. It is used to study the DNS polymerase from spinach leaf extracts. It was used in isolation and separation of Pseudomonas aeruginosa membranes by density sucrose gradient centrifugation.
Uses
Protease inhibitor.
General Description
p-Toluenesulfonyl fluoride is a peroxygen bleach activator and is also useful in the treatment of Alzheimer′s disease.
P-TOLUENESULFONYL FLUORIDESupplier
Meryer (Shanghai) Chemical Technology Co., Ltd.
- Tel
- 4006608290; 18621169109
- market03@meryer.com
Alfa Aesar
- Tel
- 400-6106006
- saleschina@alfa-asia.com
Energy Chemical
- Tel
- 021-021-58432009 400-005-6266
- sales8178@energy-chemical.com
Shanghai Hanhong Scientific Co.,Ltd.
- Tel
- 021-54306202 13764082696;
- info@hanhongsci.com
Tianjin heowns Biochemical Technology Co., Ltd.
- Tel
- 400 638 7771
- sales@heowns.com
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P-TOLUENESULFONYL FLUORIDE(455-16-3)Related Product Information
- P-TOLUENESULFINIC ACID
- p-Toluenesulfonic acid
- p-Toluenesulfonic acid monohydrate
- toluene-4-sulfonic acid 3-Methanesulfonyl-propyl ester
- BENZENESULFONYL FLUORIDE
- Phenylmethylsulfonyl fluoride
- 4-(2-Aminoethyl)benzenesulfonylfluoride hydrochloride
- P-TOLUENESULFONYL FLUORIDE
- 5'-P-FLUOROSULFONYL-BENZOYLADENOSINE HYDROCHLORIDE
- SULFORHODAMINE B 5-ACID FLUORIDE
- 4-(FLUOROSULFONYL)BENZOYL CHLORIDE
- 4-(FLUOROSULFONYL)BENZOIC ACID
- 4-(CHLOROMETHYL)BENZENESULPHONYL FLUORIDE
- 2,4,6-TRIMETHYLBENZENESULFONYL FLUORIDE
- 4-Fluorosulfonyl-3-methoxy-benzoic acid
- 4-(2-HYDROXY-1,1-DIMETHYL-ETHYL)-BENZENESULFONYL FLUORIDE
- SULFORHODAMINE Q 5-ACID FLUORIDE
- 4'-METHYLBIPHENYL-4-SULFONYLFLUORIDE