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L-Phenylglycine

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L-Phenylglycine Basic information

Product Name:
L-Phenylglycine
Synonyms:
  • H-PHG-OH
  • H-(PHENYL)GLY-OH
  • H-L-PHG-OH
  • (+)-L-ALPHA-PHENYLGLYCINE
  • L-(+)-ALPHA-PHENYLGLYCINE
  • L(+)-ALPHA-AMINOPHENYLACETIC ACID
  • L-ALPHA-AMINOPHENYLACETIC ACID
  • L-AMINOPHENYLACETIC ACID
CAS:
2935-35-5
MF:
C8H9NO2
MW:
151.16
EINECS:
220-909-8
Product Categories:
  • Amino Acids
  • Phenylglycine [Phg]
  • GLYCINESCAFFOLD
  • Amino ACIDS SERIES
  • Aromatic Phenylacetic Acids and Derivatives
  • Unusual Amino Acids
Mol File:
2935-35-5.mol
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L-Phenylglycine Chemical Properties

Melting point:
>300 °C(lit.)
alpha 
157 º (c=2, 2N HCl)
Boiling point:
273.17°C (rough estimate)
Density 
1.2023 (rough estimate)
refractive index 
158 ° (C=1, 1mol/L HCl)
Flash point:
150 °C
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
solubility 
Aqueous Acid, Aqueous Base
pka
1.83(at 25℃)
form 
Fine Crystalline Powder
color 
White
optical activity
[α]20/D +155°, c = 1 in 1 M HCl
Merck 
14,7291
BRN 
2208675
InChIKey
ZGUNAGUHMKGQNY-ZETCQYMHSA-N
CAS DataBase Reference
2935-35-5(CAS DataBase Reference)
EPA Substance Registry System
L-Phenylglycine (2935-35-5)
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Safety Information

Safety Statements 
22-24/25
WGK Germany 
3
TSCA 
Yes
HS Code 
29224995

MSDS

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L-Phenylglycine Usage And Synthesis

Description

L-Phenylglycine is an amide that belongs to the group of pyridoxal phosphate analogues. It has been shown to be a response element for enzymes and natural compounds in Escherichia coli and Saccharomyces cerevisiae. It inhibits aminotransferase activity, dopamine synthesis, and microbial metabolism in these organisms. This compound also has a structural analysis that includes x-ray diffraction data, which can be used to identify its three-dimensional structure.

Chemical Properties

White crystalline powder

Uses

L-(+)-2-Phenylglycine is a derivative of Glycine (G615990), the smallest of all the amino acids, and is also used to treat schizophrenia, stroke, and benign prostatic hyperplasia. L-(+)-2-Phenylglycine is also used as an N-linked side chain of an SMTP (Stachybotrys microspora tripenyl phenols) congener, which was potent in enhancing plasminogen activation in S. microspora.

Definition

ChEBI: The S stereoisomer of alpha-phenylglycine.

Purification Methods

Crystallise it from EtOH. [Kaneko J Chem Soc Jpn 60 538 1939, Rudman et al. J Am Chem Soc 74 551 1952, Greenstein & Winitz The Chemistry of the Amino Acids J. Wiley, Vol 3 pp 2694-2697 1961, Beilstein 14 III 1187, 14 IV 1317.]

L-Phenylglycine Preparation Products And Raw materials

Raw materials

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