Basic information Safety Supplier Related

BISINDOLYLMALEIMIDE II

Basic information Safety Supplier Related

BISINDOLYLMALEIMIDE II Basic information

Product Name:
BISINDOLYLMALEIMIDE II
Synonyms:
  • BISINDOLYLMALEIMIDE II
  • 3-(1H-Indol-3-yl)-4-[1-[2-(1-methyl-2-pyrrolidinyl)ethyl]-1H-indol-3-yl]-1H-pyrrole-2,5-dione
  • 2-[1-[2-(1-METHYLPYRROLIDINO)ETHYL]-1H-INDOL-3-YL]-3-(1H-INDOL-3-YL)MALEIMIDE
  • 3-(1H-indol-3-yl)-4-[1-[2-(1-methylpyrrolidin-2-yl)ethyl]indol-3-yl]pyrrole-2,5-dione
  • 1H-Pyrrole-2,5-dione, 3-(1H-indol-3-yl)-4-[1-[2-(1-methyl-2-pyrrolidinyl)ethyl]-1H-indol-3-yl]-
CAS:
137592-45-1
MF:
C27H26N4O2
MW:
438.52
Product Categories:
  • Enzyme Inhibitors by Enzyme
  • Kinase/Phosphatase Biology
  • P to
  • Protein Kinase C (PKC)Cell Signaling and Neuroscience
  • Protein kinase CSerine/Threonine Kinase Biology
  • Protein Kinase Inhibitors
  • Protein Kinase InhibitorsPeptides for Cell Biology
  • Protein Kinase Related Peptides
  • Serine/Threonine Kinase Inhibitors
Mol File:
Mol File
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BISINDOLYLMALEIMIDE II Chemical Properties

Boiling point:
709.9±60.0 °C(Predicted)
Density 
1.36±0.1 g/cm3(Predicted)
storage temp. 
−20°C
solubility 
DMSO: soluble
form 
solid
pka
8.17±0.60(Predicted)
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Safety Information

WGK Germany 
3

MSDS

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BISINDOLYLMALEIMIDE II Usage And Synthesis

Uses

Bisindolylmaleimide II, is a potent ATP-competitive protein kinase C (PKC) inhibitor. In addition it inhibits PDK1 (IC50 = 14 μM), an important kinase in the insulin signaling pathway, and PKA (IC50 = 2.94 μM).

storage

-20°C

BISINDOLYLMALEIMIDE IISupplier

3B Pharmachem (Wuhan) International Co.,Ltd.
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