Mafenide hydrochloride CAS#: 138-37-4

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Mafenide hydrochloride

Basic information Safety Supplier Related

Mafenide hydrochloride Basic information

Product Name:

Mafenide hydrochloride

Synonyms:

masudin
morfanil
p-aminomethylphenylsulfonamidehydrochloride
sulfamylonhydrochloride
sulfbenzaminehydrochloride
MARFANIL
MARFANIL HYDROCHLORIDE
MAFENIDE HYDROCHLORIDE

CAS:

138-37-4

MF:

C7H11ClN2O2S

MW:

222.69

EINECS:

205-325-3

Mol File:

138-37-4.mol

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Mafenide hydrochloride Chemical Properties

Melting point:: 261-263 °C(lit.)
storage temp.: Inert atmosphere,Room Temperature
solubility: DMSO (Slightly), Methanol (Slightly)
color: White
Merck: 13,5671
InChIKey: SIACJRVYIPXFKS-UHFFFAOYSA-N
CAS DataBase Reference: 138-37-4(CAS DataBase Reference)

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Safety Information

Hazard Codes: Xn
Risk Statements: 42/43
Safety Statements: 22-36/37-45
WGK Germany: 2
RTECS: XT5425000
HS Code: 29350090
Toxicity: LD50 in rats, mice (mg/kg): 1170, 900 i.v. (Skulan, Hoppe)

MSDS

Language:English Provider:SigmaAldrich

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Mafenide hydrochloride Usage And Synthesis

Uses

Antibacterial;Inhibitor of folic acid biosynthesis

Purification Methods

Crystallise the salt from dilute HCl or 95% EtOH and dry it in a vacuum at 100o. It is an antibacterial. [Miller et al. J Am Chem Soc 62 2099 1940, Bergeim & Barker J Am Chem Soc 66 1459 1944.] The sulfate salt has m 254-255o (from aqueous EtOH). [Beilstein 14 III 2223, 14 IV 2799.]

Mafenide hydrochloride Preparation Products And Raw materials

Raw materials

Etanol Hydrochloric acid Ethyl acetate Sulfuric acid Dichloromethane Chloroform Triethylamine Ammonia Acetyl chloride Chlorosulfonic acid Benzylamine

Mafenide hydrochlorideSupplier

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