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Fluotrimazol

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Fluotrimazol Basic information

Product Name:
Fluotrimazol
Synonyms:
  • FLUOTRIMAZOL
  • FLUOTRIMAZOLE
  • 1-[(3-TRIFLUOROPHENYL)DIPHENYLMETHYL]-1,2,4-TRIAZOLE
  • 1-[Diphenyl[3-(trifluoromethyl)phenyl]methyl]-1H-1,2,4-triazole
  • 4-triazole,1-(alpha,alpha-diphenyl-m-(trifluoromethyl)benzyl)-1h-2
  • 4-triazole,1-(diphenyl-(3-(trifluoromethyl)phenyl)methyl)-1h-2
  • b6660
  • persulon
CAS:
31251-03-3
MF:
C22H16F3N3
MW:
379.38
EINECS:
250-534-5
Product Categories:
  • Alpha sort
  • E-GAlphabetic
  • F
  • FA - FLPesticides
  • Fungicides
  • Pesticides&Metabolites
  • Traizoles
Mol File:
31251-03-3.mol
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Fluotrimazol Chemical Properties

Melting point:
132°C
Boiling point:
485.6±55.0 °C(Predicted)
Density 
1.21±0.1 g/cm3(Predicted)
pka
2.15±0.10(Predicted)
BRN 
8395848
CAS DataBase Reference
31251-03-3(CAS DataBase Reference)
NIST Chemistry Reference
Fluotrimazol(31251-03-3)
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Safety Information

WGK Germany 
2
RTECS 
XZ4803020
HS Code 
29339900
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Fluotrimazol Usage And Synthesis

Chemical Properties

The pure product is white crystal. mp132℃, the solubility at 20℃ is: dichloromethane 40%, cyclohexanone 20%, toluene 10%, propylene glycol 5%, water 1.5mg/L. It is decomposed in 0.2mol/L sulfuric acid solution and stable in 0.1mol/L sodium hydroxide solution.

Uses

Fluotrimazol is a fluoride-containing azole fungicide. It is characterized by high biological activity and low toxicity, and has special effects on powdery mildews such as cucumbers, peaches, barley, and grapes.

Definition

ChEBI: Fluotrimazole is a triazole fungicide.

Synthesis

Using m-bromotrifluorotoluene as the starting material, the Grignard reagent is formed, followed by nucleophilic addition with benzophenone. Then it is hydrolyzed with ammonium chloride and reacted with 1,2,4-triazole under the protection of nitrogen to obtain Fluotrimazol.

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