2,5-Dimethoxycinnamic acid Chemical Properties

Melting point:

147-150°C

Boiling point:

267.4°C (rough estimate)

Density 

1.0627 (rough estimate)

refractive index 

1.4389 (estimate)

storage temp. 

Keep in dark place,Sealed in dry,Room Temperature

form 

powder to crystal

pka

4.40±0.10(Predicted)

color 

Light orange to Yellow to Green

CAS DataBase Reference

10538-51-9(CAS DataBase Reference)

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-37/39-37

WGK Germany 

3

HazardClass 

IRRITANT

HS Code 

29189900

MSDS

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2,5-Dimethoxycinnamic acid Usage And Synthesis

Chemical Properties

yellow powder

Uses

2,5-Dimethoxycinnamic acid can be used as a pharmaceutical intermediate, and can be used in the synthesis of vasodilators such as cinnepazide.

Preparation

Synthesis of 2,5-dimethoxycinnamic acid: 2,5-dimethoxybenzaldehyde, malonic acid and pyridine were added to 100ml three necks, piperidine was added at 90°C, refluxed for 2h, cooled to room temperature, and added 3mol/L hydrochloric acid, resulting in a large amount of white precipitate, suction filtration, the filter cake is washed with water, reconstituted with ethanol, after drying, 2,5-dimethoxycinnamic acid was obtained as pale yellow needle crystals.

Definition

ChEBI: 2,5-Dimethoxycinnamic acid is a hydroxycinnamic acid.

General Description

2,5-Dimethoxycinnamic acid forms 1:1 molecular complex with 3,5-dinitrocinnamic acid.

2,5-Dimethoxycinnamic acid(10538-51-9)Related Product Information

• Ethyl 4-methoxycinnamate
• 4-Methoxycinnamic acid
• Dimethyldimethoxysilane
• Octyl 4-methoxycinnamate
• Dimethoxymethane
• alpha-Methylcinnamic acid
• Diphenyldimethoxysilane
• 3,4,5-Trimethoxycinnamic acid
• Ascoric Acid
• 3,4-Dimethoxycinnamonitrile
• trans-2,4,5-Trimethoxycinnamic acid
• 2,3-Dimethoxycinnamic acid,2,3-Dimethoxycinnamic acid, 98+%
• 3,5-DIMETHOXYCINNAMIC ACID
• TRANS-2,4-DIMETHOXYCINNAMIC ACID,2,4-Dimethoxycinnamic acid, 98+%,2,4-DIMETHOXYCINNAMIC ACID,2,4-DIMETHOXYCINNAMIC ACID, TRANS
• TRANS-3 4-DIMETHOXYCINNAMIC ACID 98%,(E)-3',4'-dimethoxycinnamic acid
• 3,5-Dimethoxy-4-hydroxycinnamic acid, 4-Hydroxy-3,5-dimethoxycinnamic acid, Sinapic acid,4-HYDROXY-3,5-DIMETHOXYCINNAMIC ACID
• 3-[4-(Acetyloxy)-3,5-dimethoxycinnamic acid
• 2-Chloro-3,4-dimethoxycinnamic acid, 98+%,2-CHLORO-3,4-DIMETHOXYCINNAMIC ACID