FLUNIXIN MEGLUMINE CAS#: 38677-85-9

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FLUNIXIN MEGLUMINE

Basic information Safety Supplier Related

FLUNIXIN MEGLUMINE Basic information

Product Name:

FLUNIXIN MEGLUMINE

Synonyms:

2-(2-Methyl-3-trifluoromethylanilino)nicotinic Acid
2-[[2-Methyl-3-(trifluoromethyl)phenyl]amino]-3-pyridinecarboxylic Acid
Sch 14714
Flunixin VETRANAL
FlunixinMeglumineBase
3-Pyridinecarboxylic acid, 2-2-methyl-3-(trifluoromethyl)phenylamino-
2-[2-Methyl-3-(trifluoromethyl)phenylamino]nicotinic acid
FLUNIXINE MEGLUMINE SALT

CAS:

38677-85-9

MF:

C14H11F3N2O2

MW:

296.24

Product Categories:

Organics
Aromatics Compounds
Aromatics
Inhibitors
Intermediates & Fine Chemicals
Pharmaceuticals

Mol File:

38677-85-9.mol

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FLUNIXIN MEGLUMINE Chemical Properties

Melting point:: 136.6-137.4 °C
Boiling point:: 378.7±42.0 °C(Predicted)
Density: 1.403±0.06 g/cm3(Predicted)
solubility: H₂O: freely soluble
form: solid
pka: 5.82(at 25℃)
color: off-white
Stability:: Stable. Incompatible with strong bases, strong oxidizing agents.
CAS DataBase Reference: 38677-85-9(CAS DataBase Reference)
EPA Substance Registry System: 3-Pyridinecarboxylic acid, 2-[[2-methyl-3-(trifluoromethyl)phenyl]amino]- (38677-85-9)

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Safety Information

Hazard Codes: Xi,Xn
Risk Statements: 36/37/38-22
Safety Statements: 26-36
RIDADR: UN2811 6.1/PG 3
WGK Germany: 3
RTECS: LZ4367000
HS Code: 2933399990

MSDS

Language:English Provider:SigmaAldrich

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FLUNIXIN MEGLUMINE Usage And Synthesis

Chemical Properties

Crystalline Solid

Uses

Cyclooxigenase inhibitor. Anti-inflammatory; analgesic; antipyretic

Definition

ChEBI: A pyridinemonocarboxylic acid that is nicotinic acid substituted at position 2 by a 2-methyl-3-(trifluoromethyl)phenylamino group. A relatively potent non-narcotic, nonsteroidal analgesic with anti-inflammatory, anti-endotoxic and anti-pyretic properties; sed in veterinary medicine (usually as the meglumine salt) for treatment of horses, cattle and pigs.

General Description

Flunixin is classified under the group of non-steroidal anti-inflammatory drugs (NSAIDs).

in vivo

Flunixin meglumine (intravenous injection; 1.1 mg/kg; once) treatment inhibits the formation of exudate PGE2 and serum TXB2^[1].

Animal Model:	Male sheep injected with Carrageenan^[1]
Dosage:	1.1 mg/kg
Administration:	Intravenous injection; 1.1 mg/kg; once
Result:	Inhibited Carrageenan-induced exudate PGE2 formation (E_max, 100%, IC₅₀, <0.4 nM) and serum TXB2 generation (E_max, 100%, IC₅₀, 17 nM) for up to 32 h.

IC 50

COX-1: 0.55 μM (IC₅₀); COX-2: 3.24 μM (IC₅₀)

FLUNIXIN MEGLUMINESupplier

LGM Pharma

Tel: 1-(800)-881-8210
Email: inquiries@lgmpharma.com

Shanghai Hanhong Scientific Co.,Ltd.

Tel: 021-54306202 13764082696
Email: info@hanhongsci.com

Syntechem Co.,Ltd

Tel
Email: info@syntechem.com

Nanjing Sunlida Biological Technology Co., Ltd.

Tel: 025-57798810
Email: sales@sunlidabio.com

Chemwill Asia Co.,Ltd.

Tel: 86-21-51086038

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