2-Fluorobenzoyl chloride Chemical Properties

Melting point:

4 °C (lit.)

Boiling point:

90-92 °C/15 mmHg (lit.)

Density 

1.328 g/mL at 25 °C (lit.)

refractive index 

n20/D 1.536(lit.)

Flash point:

180 °F

storage temp. 

Inert atmosphere,Room Temperature

solubility 

Chloroform (Slightly)

form 

Liquid

Specific Gravity

1.328

color 

Clear colorless to faintly colored

Water Solubility 

Decomposition

Sensitive 

Lachrymatory

BRN 

636864

CAS DataBase Reference

393-52-2(CAS DataBase Reference)

NIST Chemistry Reference

Benzoyl chloride, 2-fluoro-(393-52-2)

EPA Substance Registry System

o-Fluorobenzoyl chloride (393-52-2)

Safety Information

Hazard Codes 

C

Risk Statements 

34-37-36/37-14

Safety Statements 

26-36/37/39-45-28A-27

RIDADR 

UN 3265 8/PG 2

WGK Germany 

3

RTECS 

DM6640000

F 

10-19-21

Hazard Note 

Corrosive/Lachrymatory

TSCA 

Yes

HazardClass 

8

PackingGroup 

II

HS Code 

29163900

Hazardous Substances Data

393-52-2(Hazardous Substances Data)

MSDS

• Language:English Provider:o-Fluorobenzoyl chloride
• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS
• Language:English Provider:ALFA

2-Fluorobenzoyl chloride Usage And Synthesis

Chemical Properties

clear colorless to faintly colored liquid

Uses

2-Fluorobenzoyl Chloride (cas# 393-52-2) is a compound useful in organic synthesis.

Uses

2-Fluorobenzoyl chloride has been used in the preparation of 3-(N-Hydroxycarbamimidoyl)-benzoic acid methyl ester. It has been used to develop an hollow-fiber liquid phase microextraction with in situ derivatization method coupled with HPLC-UV for the determination of metformin hydrochloride in biological fluids.

General Description

Colorless liquid.

Air & Water Reactions

Decomposes in water to form HCl with generation of heat

Reactivity Profile

2-Fluorobenzoyl chloride is sensitive to moisture. Incompatible with water, alcohol, bases (including amines) and with oxidizing agents . May react vigorously or explosively if mixed with diisopropyl ether or other ethers in the presence of trace amounts of metal salts [J. Haz. Mat., 1981, 4, 291].

Fire Hazard

2-Fluorobenzoyl chloride is combustible.

2-Fluorobenzoyl chloride(393-52-2)Related Product Information

• Benzoyl chloride
• p-Toluoyl chloride
• Choline chloride
• 2,3,4,5-Tetrafluorobenzoyl chloride
• 1-Fluoro-2-nitrobenzene
• 4-Chlorobenzoyl chloride
• Sodium chloride
• 2-Fluoroaniline
• Calcium chloride
• alpha-Chloro-o-fluorotoluene
• 2-Fluorobenzoic acid
• 2-(Trifluoromethyl)benzoic acid
• Polyvinyl chloride
• Ammonium chloride
• Mepiquat chloride
• Benzyl chloride
• 3-Methylbenzoyl chloride
• 2-Bromobenzotrifluoride