Basic information Safety Supplier Related

Cyclopropene Cyanine 7 amine

Basic information Safety Supplier Related

Cyclopropene Cyanine 7 amine Basic information

Product Name:
Cyclopropene Cyanine 7 amine
Synonyms:
  • Cyclopropene Cyanine 7 amine
CAS:
1650559-73-1
MF:
C43H60Cl2N4O
MW:
719.88
Mol File:
1650559-73-1.mol
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Cyclopropene Cyanine 7 amine Chemical Properties

solubility 
Soluble in DMSO, DMF, DCM
Appearance
Green solid
ex/em
740/770 nm (MeOH/PBS)
ε(extinction coefficient)
199000 L⋅mol−1⋅cm−1
Φ(quantum yield)
0.3
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Cyclopropene Cyanine 7 amine Usage And Synthesis

Description

Cy7 amine is a functionalized cyanine dye containing a free amine group, which can be conjugated with a variety of functionalities, including NHS esters, and epoxides. Cyanine7 is a far red dye ideal for live organism imaging and applications requiring low fluorescence background.

Chemical Properties

Appearance: Green solid
ex/em: 740/770 nm (MeOH/PBS)
Extinction coefficient (ε): 199000 L??mol??1??cm??1
Quantum yield (Φ): 0.3

Uses

Cyanine 7-amine (chloride hydrochloride) can be used to label cationic nanoparticles (NPs) or to NP conjugates (NPCs). It can track the residence time and clearance of nanoparticles in the body[1].

References

[1] Melgar-Asensio I, et al. Extended Intravitreal Rabbit Eye Residence of Nanoparticles Conjugated With Cationic Arginine Peptides for Intraocular Drug Delivery: In Vivo Imaging. Invest Ophthalmol Vis Sci. 2018 Aug 1;59(10):4071-4081. DOI:10.1167/iovs.18-24087

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