POTASSIUM 2-METHYL-2-BUTOXIDE Chemical Properties

Melting point:

>160°C dec

Boiling point:

81°C

Density 

0.90 g/mL at 20 °C

vapor pressure 

0.001-0.49Pa at 20-90℃

Flash point:

4°C

storage temp. 

Inert atmosphere,Room Temperature

solubility 

soluble in THF, DME, aromatic hydrocarbons

form 

Liquid

Specific Gravity

0.8

Water Solubility 

Reacts with water.

Sensitive 

Moisture Sensitive

Hydrolytic Sensitivity

7: reacts slowly with moisture/water

BRN 

4149025

Exposure limits

ACGIH: TWA 20 ppm
OSHA: Ceiling 300 ppm; TWA 200 ppm
NIOSH: IDLH 500 ppm; TWA 100 ppm(375 mg/m3); STEL 150 ppm(560 mg/m3)

InChIKey

ZRLVQFQTCMUIRM-UHFFFAOYSA-N

EPA Substance Registry System

2-Butanol, 2-methyl-, potassium salt (41233-93-6)

Safety Information

Hazard Codes 

F,C

Risk Statements 

11-14-34-48/20-63-65-67-40-37-19

Safety Statements 

26-36/37/39-43-45-62-16

RIDADR 

UN 2924 3/PG 2

WGK Germany 

3

F 

1-10

TSCA 

Yes

HazardClass 

3

PackingGroup 

II

MSDS

• Language:English Provider:SigmaAldrich
• Language:English Provider:ALFA

POTASSIUM 2-METHYL-2-BUTOXIDE Usage And Synthesis

Uses

Potassium tert-pentyloxide is used in wide range of applications in organic synthesis, agrochemicals, pharmaceuticals, colorants and aroma chemicals. It is also used in manufacturing detergents and biodiesel. They also act as catalysts in polymerization and isomerizations.

Uses

Potassium tert-pentoxide solution has been used as a base to synthesize [RuClPh(CO)(H₂IMes)(PCy₃)] from second-generation Grubbs metathesis catalyst, [RuCl₂(=CHPh)(H₂IMes)(PCy₃)], (where H₂IMes is 1,3-dimethyl-4,5-dihydroimidazol-2-ylidene and PCy₃ is tricyclohexylphosphine) and benzyl alcohol. This complex is a solid, air-stable and highly active isomerization catalyst.

Synthesis

The Preparative Method of Potassium 2-Methyl-2-butoxide: amber-coloured 0.15-0.20 M EtCMe2OH solutions of the reagent are prepared in situ by refluxing oxide-free potassium metal in the anhydrous alcohol for 3-4 h. Solutions of the base, which are 1.0-2.0 M in THF, benzene, or toluene, are prepared by treating oil-free Potassium Hydride with an equivalent amount of anhydrous t-pentyl alcohol in the anhydrous solvent under an inert atmosphere.

Precautions

Solutions should be handled with the same precautions used for solutions of t-BuOK (see Potassium t-Butoxide). Avoid contact with the eyes, skin, and clothing. Conduct all reactions under a dry nitrogen or argon atmosphere. In the absence of air and moisture, solutions of the base in benzene or toluene may be stored in a refrigerator for up to 1 year without significant deterioration. However, for critical experiments, it is recommended that the reagent be freshly prepared. Use in a fume hood.

POTASSIUM 2-METHYL-2-BUTOXIDE(41233-93-6)Related Product Information

• Sodium carbonate
• Sodium tert-butoxide
• Magnesium tert-butoxide
• Sodium tert-pentoxide
• Lithium tert-butoxide
• ISOBUTYLLITHIUM
• PENTYLMAGNESIUM CHLORIDE
• tert-Butyllithium
• Potassium tert-butoxide
• POTASSIUM ISOPROPOXIDE
• POTASSIUM 2-METHYL-2-BUTOXIDE
• 2-Methyl-2-butanol