N-Acetylglycine Chemical Properties

Melting point:

207-209 °C (lit.)

Boiling point:

218.88°C (rough estimate)

Density 

1.3886 (rough estimate)

refractive index 

1.4540 (estimate)

storage temp. 

Sealed in dry,Room Temperature

solubility 

26.3g/l

pka

3.669(at 25℃)

form 

Crystalline Powder

color 

White

Water Solubility 

2.7 g/100 mL (15 ºC)

Merck 

14,80

BRN 

774114

InChIKey

OKJIRPAQVSHGFK-UHFFFAOYSA-N

CAS DataBase Reference

543-24-8(CAS DataBase Reference)

NIST Chemistry Reference

Glycine, N-acetyl-(543-24-8)

EPA Substance Registry System

Glycine, N-acetyl- (543-24-8)

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

22-24/25-36-26

WGK Germany 

3

TSCA 

Yes

HazardClass 

IRRITANT

HS Code 

29241900

MSDS

• Language:English Provider:N-Acetylglycine
• Language:English Provider:ACROS
• Language:English Provider:SigmaAldrich
• Language:English Provider:ALFA

N-Acetylglycine Usage And Synthesis

Chemical Properties

white to light yellow crystal powde

Uses

N-Acetyl-glycine is a derivative of Glycine (G615990). It is an intermediate used to synthesize rac 3-O-Methyl DOPA (M303805) which is an impurity of Levodopa.

Definition

ChEBI: An N-acylglycine where the acyl group is specified as acetyl.

Purification Methods

N-Acetylglycine is treated with acid-washed charcoal and recrystallised three times from water or EtOH/Et2O and is dried in vacuo over KOH [King & King J Am Chem Soc 78 1089 1956]. [Beilstein 4 IV 2399.]

N-Acetylglycine(543-24-8)Related Product Information

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