ETOXAZOLE Chemical Properties

Melting point:

101-102°

Boiling point:

449.1±45.0 °C(Predicted)

Density 

1.15±0.1 g/cm3(Predicted)

Flash point:

457℃

storage temp. 

Sealed in dry,2-8°C

solubility 

Chloroform (Slightly), Methanol (Slightly)

pka

2.04±0.70(Predicted)

color 

White to Off-White

BRN 

8930214

Stability:

Hygroscopic

InChI

InChI=1S/C21H23F2NO2/c1-5-25-18-11-13(21(2,3)4)9-10-14(18)17-12-26-20(24-17)19-15(22)7-6-8-16(19)23/h6-11,17H,5,12H2,1-4H3

InChIKey

IXSZQYVWNJNRAL-UHFFFAOYSA-N

SMILES

O1CC(C2=CC=C(C(C)(C)C)C=C2OCC)N=C1C1=C(F)C=CC=C1F

EPA Substance Registry System

Etoxazole (153233-91-1)

Safety Information

Hazard Codes 

N

Risk Statements 

50/53

Safety Statements 

60-61

RIDADR 

UN 3077 9 / PGIII

WGK Germany 

3

RTECS 

RP6795100

Hazardous Substances Data

153233-91-1(Hazardous Substances Data)

Toxicity

LD50 in rats (mg/kg): >5000 orally; >2000 dermally; LC50 (96 hr) in Japanese carp: 0.89 mg/l (Ishida)

ETOXAZOLE Usage And Synthesis

Description

Etoxazole is an organofluorine acaricide. It induces toxicity in two-spotted spider mite (T. urticae) larvae (LC₅₀ = 0.036 mg/L for the London reference strain) through inhibition of chitin synthase 1. It reduces acetylcholinesterase (AChE) activity in the freshwater fish O. niloticus in a concentration-dependent manner. Etoxazole (2.2-22 mg/kg per day) inhibits the activity of catalase, glutathione peroxidase (GPX), and AChE in the liver and kidneys of rats in a dose-dependent manner. Formulations containing etoxazole have been used for the control of mites in agriculture.

Chemical Properties

Pale-yellow liquid when pure or reddish-brown liquid or semisolid as a technical product. Mild odor.

Uses

Acaricide.

Uses

Isotope labelled Etoxazole is a acaricide/insecticide that works via chitin biosynthesis inhibition for the control of mites. Used as a standard for Pesticide detection. Useful in cannabis testing kits as a component of pesticide mixes (P698235).

Definition

ChEBI: Etoxazole is an organofluorine acaricide.

Potential Exposure

Aromatic hydrocarbon; Thiazole fungicide Etridiazole is a fungicide used in some countries as a seed treatment on barley, beans, corn, cotton, peanuts, peas, sorghum, soybeans, safflower, and wheat. It is also used on cotton for in-furrow application at planting, on ornamental plants and shrubs by horticultural nurseries, on nonbearing citrus and nonbearing coffee, and for golf course fairways, tees and greens. Some states hold Special Local Need registrations for use on tobacco transplants

Shipping

UN2810 Toxic liquids, organic, n.o.s., Hazard Class: 6.1; Labels: 6.1-Poisonous materials, Technical Name Required. Military driver shall be given full and complete information regarding shipment and conditions in case of emergency. AR 50-6 deals specifically with the shipment of chemical agents. Shipments of agent will be escorted in accordance with AR 740-32.

Incompatibilities

Diazo compounds can detonate. This applies in particular to organic azides that have been sensitized by the addition of metal salts or strong acids. Toxic gases are formed by mixing materials of this class with acids, aldehydes, amides, carbamates, cyanides, inorganic fluorides, halogenated organics, isocyanates, ketones, metals, nitrides, peroxides, phenols, epoxides, acyl halides, and strong oxidizing or reducing agents. Flammable gases are formed by mixing materials in this group with alkali metals. Explosive combination can occur with strong oxidizing agents, metal salts, peroxides, and sulfides. This chemical is sensitive to prolonged exposure to heat. This chemical is incompatible with strong oxidizing agents

Waste Disposal

Incineration would be an effective disposal procedure where permitted. If an efficient incinerator is not available, the product should be mixed with large amounts of combustible material and contact with the smoke should be avoided. In accordance with 40CFR165, follow recommendations for the disposal of pesticides and pesticide containers

ETOXAZOLE(153233-91-1)Related Product Information

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