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4-Bromobiphenyl

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4-Bromobiphenyl Basic information

Product Name:
4-Bromobiphenyl
Synonyms:
  • (4-bromophenyl)benzene
  • 1,1’-(biphenyl,-bromo-
  • 1,1’-Biphenyl,4-bromo-
  • 1,1’-biphenyl,-bromo-(4-bromobiphenyl)
  • 1’-Biphenyl,4-bromo-1
  • 4-Biphenyl bromide
  • 4-biphenylylbromide
  • 4-Brom-biphenyl
CAS:
92-66-0
MF:
C12H9Br
MW:
233.1
EINECS:
202-176-6
Product Categories:
  • blocks
  • Bromides
  • Aromatic Compounds
  • Liquid Crystal intermediates
  • Biphenyl derivatives
  • Biphenyl & Diphenyl ether
  • Yellow crystalline powder
  • A-BAnalytical Standards
  • Alpha Sort
  • AromaticsAlphabetic
  • B
  • BI - BZChemical Class
  • Bromo
  • Chemical Class
  • Halogenated
  • Volatiles/ Semivolatiles
  • Aryl
  • C9 to C12
  • Halogenated Hydrocarbons
  • bc0001
  • 92-66-0
Mol File:
92-66-0.mol
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4-Bromobiphenyl Chemical Properties

Melting point:
82-86 °C(lit.)
Boiling point:
310 °C(lit.)
Density 
0.9327
refractive index 
1.6565 (estimate)
Flash point:
143 °C
storage temp. 
Sealed in dry,Room Temperature
solubility 
dioxane: soluble1g/10 mL, clear, colorless to very faintly yellow
form 
Crystalline Flakes
color 
Almost white to slightly yellow
Water Solubility 
Insoluble
BRN 
1907453
Stability:
Stable. Incompatible with oxidizing agents.
InChIKey
PKJBWOWQJHHAHG-UHFFFAOYSA-N
CAS DataBase Reference
92-66-0(CAS DataBase Reference)
NIST Chemistry Reference
1,1'-Biphenyl, 4-bromo-(92-66-0)
EPA Substance Registry System
4-Bromobiphenyl (92-66-0)
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Safety Information

Hazard Codes 
Xi,N,Xn
Risk Statements 
36/37/38-50/53-41-37/38-22
Safety Statements 
22-24/25-37/39-26-61-60-39
RIDADR 
UN 3152 9/PG 2
WGK Germany 
3
RTECS 
DV1750100
TSCA 
T
HazardClass 
IRRITANT
PackingGroup 
HS Code 
29036990

MSDS

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4-Bromobiphenyl Usage And Synthesis

Chemical Properties

White powder

Uses

4-Bromobiphenyl is used as halogenated hydrocarbon and Intermediates of Liquid Crystals. It is also used in used in the synthesis of 4-biphenylthiolate.

Uses

4-Bromobiphenyl is used as a reagent in the synthesis of spirooxindole derivatives for use as AMPK activators.  It is also used as a reagent in the preparation of indenoindole derivatives as organic electroluminescent device materials.

General Description

Colorless crystals. Insoluble in water.

Air & Water Reactions

Insoluble in water.

Reactivity Profile

4-Bromobiphenyl may be sensitive to light, and it can react with oxidizing materials.

Fire Hazard

Combustible.

Synthesis

Into a 250 ml reactor equipped with magnetic agitation means, a condenser, a dropping funnel, and a thermometer, the following materials were introduced:
(i) 15.4 g biphenyl (0.1 M);
(ii) 100 ml solvent
at ambient temperature Then, over 10 min, the bromine was poured therein (39.2 g/0.22 M), whereupon the mixture was agitated for a varying period of time at ambient temperature. Upon completion of the reaction, the excess bromine was consumed by sodium or potassium sulfite or bisulfite. The organic phase was washed, dried and diluted to a given volume, and analyzed by CPG to give 4-Bromobiphenyl.

Purification Methods

Crystallise the biphenyl from abolute EtOH and dry it in vacuo.[Beilstein 5 IV 1819.]

4-Bromobiphenyl Preparation Products And Raw materials

Raw materials

Preparation Products

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