HNGF6A Chemical Properties

Density 

1.44±0.1 g/cm3(Predicted)

storage temp. 

Store at -20°C

form 

Powder

Water Solubility 

Soluble to 1 mg/ml in water

Sequence

Met-Ala-Pro-Arg-Gly-Ala-Ser-Cys-Leu-Leu-Leu-Leu-Thr-Gly-Glu-Ile-Asp-Leu-Pro-Val-Lys-Arg-Arg-Ala

HNGF6A Usage And Synthesis

Uses

HNGF6A is a humanin analogue. HNGF6A increases glucose-stimulated insulin secretion and glucose metabolism, and has the potential for diabetes research. HNGF6A inhibits of ROS production during oxidative stress. HNGF6A can prevent endothelial dysfunction and atherosclerosis in vivo[1][2].

References

[1] Yun K Oh, et al. Humanin preserves endothelial function and prevents atherosclerotic plaque progression in hypercholesterolemic ApoE deficient mice. Atherosclerosis. 2011 Nov;219(1):65-73. DOI:10.1016/j.atherosclerosis.2011.06.038
[2] Regina Kuliawat, et al. Potent humanin analog increases glucose-stimulated insulin secretion through enhanced metabolism in the β cell. FASEB J. 2013 Dec;27(12):4890-8. DOI:10.1096/fj.13-231092

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