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(-)-2,2'-METHYLENEBIS[(3AS,8AR)-3A,8A-DIHYDRO-8H-INDENO[1,2-D]OXAZOLE]

Basic information Safety Supplier Related

(-)-2,2'-METHYLENEBIS[(3AS,8AR)-3A,8A-DIHYDRO-8H-INDENO[1,2-D]OXAZOLE] Basic information

Product Name:
(-)-2,2'-METHYLENEBIS[(3AS,8AR)-3A,8A-DIHYDRO-8H-INDENO[1,2-D]OXAZOLE]
Synonyms:
  • (3aS,8aR)-2-[(3aS,8aR)-3aH,8H,8aH-Indeno[1,2-d][1,3]oxazol-2-ylmethyl]-3aH,8H,8aH-indeno[1,2-d][1,3]oxazole
  • [3as-[2(3′Ar*,8′As*),3′AΑ,8′AΑ]]-()-2,2′-Methylenebis[3a,8a-Dihydro-8H-Inden
  • [3AS-[2(3'A R*,8'A S*),3'A-ALPHA,8'A-ALPHA]]-(-)-2,2'-METHYLENEBIS[3A,8A-DIHYDRO-8 H-INDENO[1,2-D]OXAZOLE]
  • (-)-2,2'-Methylenebis
  • (3aS,3′aS,8aR,8′aR)-(-)-2,2′-Methylenebis[3a,8a-dihydro-8H-indeno[1,2-d]oxazole]
  • Bis((3aS,8aR)-8,8a-dihydro-3aH-indeno[1,2-d]oxazol-2-yl)methane
  • 8H-Indeno[1,2-d]oxazole,2,2'-Methylenebis[3a,8a-dihydro-, (3aS,3'aS,8aR,8'aR)-
  • (-)-2,2'-Methylenebis[(3AS,8AR)-3A,8A-Dihydro-8H-Indeno[1,2-D]Oxazole],98%
CAS:
175166-49-1
MF:
C21H18N2O2
MW:
330.38
Product Categories:
  • Asymmetric Synthesis
  • Synthetic Organic Chemistry
  • BOX
  • Chiral Catalysts, Ligands, and Reagents
  • Privileged Ligands and Complexes
  • BOX series
  • Chiral Nitrogen
Mol File:
175166-49-1.mol
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(-)-2,2'-METHYLENEBIS[(3AS,8AR)-3A,8A-DIHYDRO-8H-INDENO[1,2-D]OXAZOLE] Chemical Properties

Melting point:
224 °C
Boiling point:
493.2±45.0 °C(Predicted)
Density 
1.48±0.1 g/cm3(Predicted)
refractive index 
-360 ° (C=1, CH2Cl2)
storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
solubility 
almost transparency in Dichloromethane
form 
powder to crystal
pka
5.47±0.20(Predicted)
color 
White to Almost white
optical activity
[α]22/D 355°, c = 3.7 in chloroform
InChIKey
BDHSVQLSNIGJNC-JYWFKMLOSA-N
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Safety Information

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
WGK Germany 
3
HS Code 
29349990
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(-)-2,2'-METHYLENEBIS[(3AS,8AR)-3A,8A-DIHYDRO-8H-INDENO[1,2-D]OXAZOLE] Usage And Synthesis

Chemical Properties

White powder

Uses

(3aS,3′aS,8aR,8′aR)-2,2′-Methylenebis[3a,8a-dihydro-8H-indeno[1,2-d]oxazole] can be used as a chiral ligand:

  • In the preparation of oxazole α-hydroxy esters through intermolecular Alder-Ene reaction.
  • In the atom transfer radical polymerization reactions of methyl methacrylate.
  • In the copper-catalyzed synthesis of isoxazolidine derivatives by reacting nitrone with α,β-unsaturated acyl?phosphonate.

(-)-2,2'-METHYLENEBIS[(3AS,8AR)-3A,8A-DIHYDRO-8H-INDENO[1,2-D]OXAZOLE]Supplier

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