Basic information Safety Supplier Related

3'-O-METHYLURIDINE

Basic information Safety Supplier Related

3'-O-METHYLURIDINE Basic information

Product Name:
3'-O-METHYLURIDINE
Synonyms:
  • 3'-O-METHYLURIDINE
  • 3'-O-Me-Ur
  • Uridine, 3'-O-methyl-
  • 3’-OMe-U
  • 4-[1-[(2-methylphenyl)methyl]benzimidazol-2-yl]-1,2,5-oxadiazol-3-amine
  • 3'-OMe-Uridine
  • 1-((2R,3R,4S,5R)-3-Hydroxy-5-(hydroxymethyl)-4-methoxytetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione
  • 1-((2R,3R,4R,5R)-3-Hydroxy-5-(hydroxymethyl)-4-methoxytetrahydro furan-2-yl)pyrimidine-2,4(1H,3H)-dione
CAS:
6038-59-1
MF:
C10H14N2O6
MW:
258.23
Product Categories:
  • Biochemicals and Reagents
  • Nucleoside Analogs
  • Nucleosides, Nucleotides, Oligonucleotides
  • Modified(deoxy)nucleoside
  • Nucleosides-3'-OMe Nucleosides
Mol File:
6038-59-1.mol
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3'-O-METHYLURIDINE Chemical Properties

Melting point:
142-145 °C
Density 
1.53±0.1 g/cm3(Predicted)
storage temp. 
−20°C
pka
9.39±0.10(Predicted)
InChI
InChI=1S/C10H14N2O6/c1-17-8-5(4-13)18-9(7(8)15)12-3-2-6(14)11-10(12)16/h2-3,5,7-9,13,15H,4H2,1H3,(H,11,14,16)/t5-,7-,8-,9-/m1/s1
InChIKey
YKNATSNMFLEFRB-ZOQUXTDFSA-N
SMILES
OC[C@H]1O[C@@H](N2C=CC(=O)NC2=O)[C@H](O)[C@@H]1OC
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Safety Information

WGK Germany 
3
HS Code 
29349990

MSDS

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3'-O-METHYLURIDINE Usage And Synthesis

Uses

3’-O-Methyluridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

References

[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005

3'-O-METHYLURIDINESupplier

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