DL-GAMMA-AMINO-B-HYDROXYBUTYRIC ACIDCRYS TALLINE Chemical Properties

Melting point:

223 °C (dec.) (lit.)

Boiling point:

222.38°C (rough estimate)

Density 

1.3126 (rough estimate)

refractive index 

1.4183 (estimate)

storage temp. 

Keep in dark place,Sealed in dry,Room Temperature

solubility 

Water (Sparingly)

pka

pK1: 3.834(+1);pK2: 9.487(0) (25°C,μ=0.1)

form 

Powder

color 

White to Yellow

Water Solubility 

almost transparency

Merck 

14,444

Stability:

Hygroscopic

LogP

-1.730 (est)

EPA Substance Registry System

4-Amino-3-hydroxybutyric acid (924-49-2)

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-36

WGK Germany 

3

RTECS 

ES7015000

TSCA 

Yes

HS Code 

29224985

DL-GAMMA-AMINO-B-HYDROXYBUTYRIC ACIDCRYS TALLINE Usage And Synthesis

Chemical Properties

White crystalline powder

Uses

antiepileptic

Uses

Reduces uptake of iodine by the thyroid glands in animals. Antispasmodic

Definition

ChEBI: Gamma-amino-beta-hydroxybutyric acid is a gamma-amino acid comprising 4-aminobutyric acid having a 2-hydroxy substituent. It is a gamma-amino acid and a 3-hydroxy monocarboxylic acid. It is functionally related to a butyric acid. It is a conjugate acid of a 4-amino-3-hydroxybutanoate. It is a tautomer of a gamma-amino-beta-hydroxybutyric acid zwitterion.

reaction suitability

reaction type: solution phase peptide synthesis

Purification Methods

Crystallise the acid from H2O or aqueous EtOH. Recrystallise it by dissolving it (CO2H), pK Est( 2) in H2O and adding MeOH or EtOH. It is not very soluble in CHCl3 or EtOAc. [Renaud & Seebach Synthesis 424 1986, Beilstein 4 IV 3187.]

DL-GAMMA-AMINO-B-HYDROXYBUTYRIC ACIDCRYS TALLINE(924-49-2)Related Product Information

• DL-Homoserine
• L-Threonine
• L-carnitine
• D-Threonine
• (R)-(-)-AMINO-3-HYDROXYBUTANOIC ACID
• (S)-(-)-4-Amino-2-hydroxybutyric acid
• D-Homoserine
• DL-Threonine hydrate(2:1)
• (S)-N-Carbobenzyloxy-4-amino-2-hydroxybutyric acid
• L(+)-allo-Threonine
• allo-DL-Threonine
• DL-4-Amino-3-hydroxybutyric acid
• 2-Hydroxy-4-amino butanoic acid
• DL-Threonine
• D(-)-allo-Threonine
• (S)-(+)-4-AMINO-3-HYDROXYBUTANOIC ACID
• 3-Hydroxybutyric acid
• L-Homoserine