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O-DESMETHYLNAPROXEN

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O-DESMETHYLNAPROXEN Basic information

Product Name:
O-DESMETHYLNAPROXEN
Synonyms:
  • Naproxen Impurity 1(Naproxen EP Impurity A)
  • (s)-6-hydroxy-α-methyl-2-naphthaleneacetic acid
  • (aS)-6-Hydroxy-α-methyl-2-naphthaleneacetic Acid
  • (S)-2-(6-Hydroxy-2-naphthyl)propionic Acid
  • (S)-6-Demethylnaproxen
  • (S)-6-O-Desmethylnaproxen
  • (S)-O-Desmethyl Naproxen
  • (aS)-6-Hydroxy-a-methyl-2-naphthaleneacetic Acid
CAS:
52079-10-4
MF:
C13H12O3
MW:
216.23
Product Categories:
  • Intermediates & Fine Chemicals
  • Metabolites & Impurities
  • Chiral Reagents
  • Pharmaceuticals
Mol File:
52079-10-4.mol
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O-DESMETHYLNAPROXEN Chemical Properties

Melting point:
182-183 °C
Boiling point:
432.1±20.0 °C(Predicted)
Density 
1.297±0.06 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
DMSO: soluble
pka
4.87±0.30(Predicted)
color 
white
BRN 
8838512
CAS DataBase Reference
52079-10-4
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Safety Information

Hazard Codes 
Xn,N
Risk Statements 
22-43-50/53
Safety Statements 
36/37-60-61
RIDADR 
UN 3077 9/PG 3
WGK Germany 
3
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O-DESMETHYLNAPROXEN Usage And Synthesis

Chemical Properties

Off-Whie to Pale Pink Solid

Uses

A metabolite of Naproxen

Uses

O-Desmethylnaproxen can be used for assaying naproxen metabolites.

Definition

ChEBI: A member of the class of naphthols that is naproxen in which the 6-methoxy group has been demethylated.

Biochem/physiol Actions

CYP2C9 metabolite of naproxen

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