3-[(2-AMINOETHYL)DITHIO]PROPIONIC ACID Chemical Properties

Melting point:

138-141oC

Boiling point:

339.5±27.0 °C(Predicted)

Density 

1.320±0.06 g/cm3(Predicted)

storage temp. 

-20°C Freezer

solubility 

Soluble in Water, DMSO

form 

A solid

pka

4.20±0.10(Predicted)

color 

White to off-white

Stability:

Hygroscopic

InChI

InChI=1S/C5H11NO2S2/c6-2-4-10-9-3-1-5(7)8/h1-4,6H2,(H,7,8)

InChIKey

HMMFDEBVQNRZLJ-UHFFFAOYSA-N

SMILES

C(O)(=O)CCSSCCN

3-[(2-AMINOETHYL)DITHIO]PROPIONIC ACID Usage And Synthesis

Description

Aminoethyl-SS-propionic acid is a cleavable compound containing a terminal amine and carboxylic acid group. The disulfide bonds can be cleaved using Dithiothreitol (DTT) reagent. The terminal amine can be reacted with carboxylic acid, activated NHS esters and other carbonyl compounds. The terminal carboxylic acid can be reacted with primary amines in the presence of activators such as EDC and HATU to form a stable amide bond.

Chemical Properties

3-[(2-AMINOETHYL)DITHIO]PROPIONIC ACID is White Solid

Uses

3-[(2-AMINOETHYL)DITHIO]PROPIONIC ACID is a useful reversible immobilization or crossliking reagent

IC 50

Disulfide Cleavable Linker; Cleavable Linker

3-[(2-AMINOETHYL)DITHIO]PROPIONIC ACID(15579-00-7)Related Product Information

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