Basic information Uses Safety Supplier Related

Ethyl 2-methoxy-5-sulfamoylbenzoate

Basic information Uses Safety Supplier Related

Ethyl 2-methoxy-5-sulfamoylbenzoate Basic information

Product Name:
Ethyl 2-methoxy-5-sulfamoylbenzoate
Synonyms:
  • Ethyl 2-methoxy-5-(sulfamoylmethyl)benzoate
  • Ethyl 2-methoxy-5-sulfamoylbenzoate
  • Ethyl 5-sulphamoyl-o-anisate
  • Sulpiride IMpurity C
  • 2-METHOXYL-5-METHYLSULFONYLBENZOIC ACID METHYL ESTER
  • Sulpiride Impurity 3(Sulpiride EP Impurity C)
  • Sulpiride EP Impurity C
  • Sulpiride Impurity C(EP)
CAS:
33045-53-3
MF:
C10H13NO5S
MW:
259.28
EINECS:
251-359-7
Product Categories:
  • FINE Chemical & INTERMEDIATES
Mol File:
33045-53-3.mol
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Ethyl 2-methoxy-5-sulfamoylbenzoate Chemical Properties

Melting point:
148-151 °C
Boiling point:
446.5±55.0 °C(Predicted)
Density 
1.317±0.06 g/cm3(Predicted)
vapor pressure 
0Pa at 25℃
storage temp. 
Refrigerator
solubility 
DMSO (Sparingly), Methanol (Slightly)
form 
Solid
pka
9.95±0.60(Predicted)
color 
White to Off-White
Water Solubility 
1.545g/L at 25℃
LogP
1.33
CAS DataBase Reference
33045-53-3(CAS DataBase Reference)
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Ethyl 2-methoxy-5-sulfamoylbenzoate Usage And Synthesis

Uses

2-Methoxy-5-sulfonamide ethyl benzoate is an important intermediate for the antipsychotic drugs sulpiride and levosulpiride. Sulpiride, chemically named N-[(1-ethyl-2-pyrrolyl)methyl]-2-methoxy-5-(aminosulfonyl)benzamide, was synthesized by the French in 1967. Due to its therapeutic effects on mental disorders and few adverse reactions, it has been used clinically both domestically and internationally for many years.

Flammability and Explosibility

Not classified

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