Bis-peg13-nhs ester CAS#: 2221949-00-2

Bis-peg13-nhs ester Basic information

Product Name:

Bis-peg13-nhs ester

Synonyms:

4,7,10,13,16,19,22,25,28,31,34,37,40-Tridecaoxatritetracontanedioic acid, 1,43-bis(2,5-dioxo-1-pyrrolidinyl) ester
Bis-dPEG13-NHS ester
Di-NHS Ester-PEG13
Bis(2,5-dioxopyrrolidin-1-yl) 4,7,10,13,16,19,22,25,28,31,34,37,40-tridecaoxatritetracontanedioate
Bis(2,5-dioxo-1-pyrrolidinyl) 4,7,10,13,16,19,22,25,28,31,34,37,40-Tridecaoxatritetracontane-1,43-dioate
COONHS-PEG13-CH2CH2COONHS
NHSOOCCH2CH2O-PEG12-CH2CH2COONHS ester

CAS:

2221949-00-2

MF:

C38H64N2O21

MW:

884.92

Mol File:

2221949-00-2.mol

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Bis-peg13-nhs ester Chemical Properties

Boiling point:: 833.0±75.0 °C(Predicted)
Density: 1.27±0.1 g/cm3(Predicted)
storage temp.: -20°C, sealed storage, away from moisture
form: Solid-Liquid Mixture
color: Colorless to off-white
InChIKey: OVDFFVRBNAHLOH-UHFFFAOYSA-N
SMILES: C(ON1C(=O)CCC1=O)(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCC(ON1C(=O)CCC1=O)=O

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Bis-peg13-nhs ester Usage And Synthesis

Uses

Bis-PEG13-NHS ester is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. Bis-PEG13-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

IC 50

PEGs; Alkyl/ether; Cleavable Linker

References

[1] John L. Magnani, et al. Highly potent multimeric e-selectin antagonists. WO2018068010A1

Bis-peg13-nhs esterSupplier

Xi'an Confluore Biological Technology Co., Ltd. Gold

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SHANGHAI FDC-CHEMICAL CO.,LTD

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TargetMol Chemicals Inc.

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Email: marketing@targetmol.com

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