Thalidomide-O-amido-PEG4-C2-NH2 hydrochloride Chemical Properties

storage temp. 

2-8°C, sealed storage, away from moisture

solubility 

Soluble in DMSO

form 

Oil

color 

Light yellow to yellow

Thalidomide-O-amido-PEG4-C2-NH2 hydrochloride Usage And Synthesis

Uses

Thalidomide-O-amido-PEG4-C2-NH2 hydrochloride, a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker, can be used in the synthesis of PROTACs[1].

IC 50

Cereblon

storage

Store at -20°C

References

[1] James Bradner, et al. Methods to induce targeted protein degradation through bifunctional molecules. WO2016105518A1.

Thalidomide-O-amido-PEG4-C2-NH2 hydrochloride(2245697-85-0)Related Product Information

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